114753-52-5Relevant articles and documents
Synthesis and evaluation of 3′-azido-2′,3′-dideoxypurine nucleosides as inhibitors of human immunodeficiency virus
Zhang, Hong-wang,Coats, Steven J.,Bondada, Lavanya,Amblard, Franck,Detorio, Mervi,Asif, Ghazia,Fromentin, Emilie,Solomon, Sarah,Obikhod, Aleksandr,Whitaker, Tony,Sluis-Cremer, Nicolas,Mellors, John W.,Schinazi, Raymond F.
scheme or table, p. 60 - 64 (2010/04/05)
Based on the promising drug resistance profile and potent anti-HIV activity of β-d-3′-azido-2′,3′-dideoxyguanosine, a series of purine modified nucleosides were synthesized by a chemical transglycosylation reaction and evaluated for their antiviral activity, cytotoxicity, and intracellular metabolism. Among the synthesized compounds, several show potent and selective anti-HIV activity in primary lymphocytes.
Synthesis of 9-(3-azido-2,3-dideoxy-β-D-erythro-pentofuranosyl)-2,6-diaminopurine (AzddDAP)
Herdewijn,Van Aerschot
, p. 855 - 858 (2007/10/02)
-