1147885-39-9Relevant articles and documents
Facile reductive amination of aldehydes with electron-deficient anilines by acyloxyborohydrides in TFA: Application to a diazaindoline scale-up
Boros, Eric E.,Thompson, James B.,Katamreddy, Subba R.,Carpenter, Andrew J.
, p. 3587 - 3590 (2009)
A scale-up of diazaindoline 1 was achieved in four stages and 32% overall yield. The key step involved rapid reductive animation of aldehyde 8 with aniline 5 by sodium triacetoxyborohydride (STAB-H) and TFA followed by ring closure of intermediate amine 9