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1148110-16-0

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1148110-16-0 Usage

Description

1-Bromo-4-(bromomethyl)-2-methoxybenzene is a chemical compound with the molecular formula C8H8Br2O. It features a benzene ring with a bromine atom at the 1 position, a bromomethyl group at the 4 position, and a methoxy group at the 2 position. 1-Bromo-4-(bromomethyl)-2-methoxybenzene is recognized for its reactivity in various chemical reactions such as substitution, addition, and coupling, which makes it a versatile and valuable component in the development of new chemical compounds.

Uses

Used in Pharmaceutical Industry:
1-Bromo-4-(bromomethyl)-2-methoxybenzene is used as an intermediate in organic synthesis for the production of various pharmaceuticals. Its unique structure and reactivity allow for the creation of a wide range of medicinal compounds, contributing to the development of new treatments and therapies.
Used in Agrochemical Industry:
In the agrochemical sector, 1-Bromo-4-(bromomethyl)-2-methoxybenzene is utilized as a key building block for synthesizing various agrochemicals. Its properties make it suitable for the development of compounds used in pest control, crop protection, and other agricultural applications.
Used in Fine Chemicals Production:
1-Bromo-4-(bromomethyl)-2-methoxybenzene also serves as an important intermediate for the production of other fine chemicals. Its versatility in chemical reactions enables the synthesis of specialty chemicals used across different industries, including fragrances, dyes, and advanced materials.
It is crucial to handle 1-Bromo-4-(bromomethyl)-2-methoxybenzene with care, as it is classified as a hazardous material due to its potential health and environmental risks. Proper safety measures should be taken during its production, use, and disposal to mitigate any risks associated with this compound.

Check Digit Verification of cas no

The CAS Registry Mumber 1148110-16-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,8,1,1 and 0 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1148110-16:
(9*1)+(8*1)+(7*4)+(6*8)+(5*1)+(4*1)+(3*0)+(2*1)+(1*6)=110
110 % 10 = 0
So 1148110-16-0 is a valid CAS Registry Number.

1148110-16-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-Bromo-4-(bromomethyl)-2-methoxybenzene

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1148110-16-0 SDS

1148110-16-0Relevant articles and documents

Discovery of EBI-907: A highly potent and orally active B-RafV600Einhibitor for the treatment of melanoma and associated cancers

Lu, Biao,Cao, Hu,Cao, Jingsong,Huang, Song,Hu, Qiyue,Liu, Dong,Shen, Ru,Shen, Xiaodong,Tao, Weikang,Wan, Hong,Wang, Dan,Yan, Yinfa,Yang, Liuqing,Zhang, Jiayin,Zhang, Lei,Zhang, Lianshan,Zhang, Minsheng

, p. 819 - 823 (2016/05/24)

A novel series of pyrazolo[3,4-c]isoquinoline derivatives was discovered as B-RafV600Einhibitors through scaffold hopping based on a literature lead PLX4720. Further SAR exploration and optimization led to the discovery of potent B-RafV600

Discovery of 6-aryl-7-alkoxyisoquinoline inhibitors of IκB kinase-β (IKK-β)

Christopher, John A.,Bamborough, Paul,Alder, Catherine,Campbell, Amanda,Cutler, Geoffrey J.,Down, Kenneth,Hamadi, Ahmed M.,Jolly, Adrian M.,Kerns, Jeffrey K.,Lucas, Fiona S.,Mellor, Geoffrey W.,Miller, David D.,Morse, Mary A.,Pancholi, Kiritkant D.,Rumsey, William,Solanke, Yemisi E.,Williamson, Rick

supporting information; experimental part, p. 3098 - 3102 (2010/03/03)

The identification and progression of a potent and selective series of isoquinoline inhibitors of IκB kinase-β (IKK-β) are described. Hit-generation chemistry based on IKK-β active-site knowledge yielded a weakly potent but tractable chemotype that was rapidly progressed into a series with robust enzyme and cellular activity and significant selectivity over IKK-α.

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