114841-44-0

Basic information

• Product Name: 2-((1H-tetrazol-5-yl)methyl)isoindoline-1,3-dione
• CAS NO: 114841-44-0
• Molecular Weight: 229.198
• Mol File: 114841-44-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-((1H-tetrazol-5-yl)methyl)isoindoline-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((1H-tetrazol-5-yl)methyl)isoindoline-1,3-dione(114841-44-0)
• EPA Substance Registry System: 2-((1H-tetrazol-5-yl)methyl)isoindoline-1,3-dione(114841-44-0)

Safety Data

• Hazardous Substances Data: 114841-44-0(Hazardous Substances Data)

Usage

Molecular structure

2-((1H-tetrazol-5-yl)methyl)isoindoline-1,3-dione has a complex molecular structure that includes a tetrazole ring and an isoindoline-1,3-dione group.

Heterocyclic compound

The presence of the tetrazole ring and the isoindoline-1,3-dione group makes this compound a heterocyclic compound, which means it contains one or more atoms of heteroelements (such as nitrogen or oxygen) in its ring structure.

Tettrazole ring

The compound contains a 1H-tetrazol-5-yl ring, which is a five-membered ring with four nitrogen atoms and one hydrogen atom. This suggests potential pharmaceutical uses, as tetrazole derivatives have been studied for their antimicrobial, antitumor, and anti-inflammatory properties.

Isoindoline-1,3-dione group

The presence of the isoindoline-1,3-dione group (a benzene ring fused with a pyridine ring and containing two carbonyl groups) indicates that the compound may be used in the synthesis of various bioactive compounds, including potential drugs.

Potential pharmaceutical applications

Due to the presence of the tetrazole ring and the isoindoline-1,3-dione group, the compound may have potential applications in medicine, such as antimicrobial, antitumor, and anti-inflammatory properties.

Further research needed

To determine the specific biological and pharmacological properties of 2-((1H-tetrazol-5-yl)methyl)isoindoline-1,3-dione, as well as its potential applications in medicine and other industries, further research and analysis are required.

Upstream product

• 3842-20-4 N-(cyanomethyl)phthalimide 
• 136918-14-4 phthalimide 

Downstream Products

• 31602-63-8 (1H-tetrazol-5-yl)methanamine 

Relevant articles and documents

Synthesis and antimicrobial activity of new tetrazoles incorporating isoindole-1,3-dione moiety and their sugar derivatives

New tetrazole derivatives linked to isoindole-1,3-dione were prepared starting from the corresponding nitrile derivatives. The substituted hydrazides, their corresponding sugar hydrazones, and the derived acyclic C-nucleoside analogs were also synthesized

Synthesis, antifungal evaluation and molecular docking studies of some tetrazole derivatives

A facile and simple protocol for the [3+2] cycloaddition of alkyl nitriles (RCN) with sodium azide (NaN3) in the presence of copper bis(diacetylcurcumin) 1,2-diamin-obenzene Schiff base complex, SiO2-[Cu-BDACDABSBC] as a heterogeneous catalyst in the presence of ascorbic acid and a solution of water/i-PrOH (50:50, V/V) media at reflux condition is described. The supported catalyst was prepared by immobilization of a copper bis(diacetylcurcumin) 1,2-diaminobenzene Schiff base complex [Cu-BDACDABSBC] on silica gel. The complex has high selectivity, catalytic activity, and recyclability. The significant features of this procedure are high yields, broad substrate scope and simple and efficient work-up procedure. According to this synthetic methodology, excellent yields of 5-substituted 1H-tetrazoles having bioactive N-heterocyclic cores were synthesized. The in vitro antifungal activities of title compounds were screened against various pathogenic fungal strains, such as Candida species involving C. albicans, C. glabrata, C. krusei, C. parapsilosis as well as filamentous fungi like Aspergillus species consisting of A. fumigatus and A. flavus. The molecular docking analysis is discussed for one most potent compound against fungi. The docking study determined a remarkable interaction between the most potent compounds and the active site of Mycobacterium P450DM.