114873-10-8Relevant articles and documents
METHODS OF TREATING LIVER FIBROSIS USING CALPAIN INHIBITORS
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Paragraph 0391, (2020/01/24)
Disclosed herein are methods of treating liver fibrosis by administering calpain inhibitors to subjects in need thereof.
Process for the preparation of substituted N-(indole-2-carbonyl)- glycinamides
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, (2008/06/13)
Processes and intermediates for preparing compounds of Formula (I).
EPOXYSUCCINIC ACID DERIVATIVES
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, (2008/06/13)
A compound of the general formula: STR1 wherein R 1 represents a carboxyl group which may optionally be esterified or amidated; R 2 represents a cyclic group which may optionally be substituted or a polar group; n is an integer of 0 to 6; R 3 represents hydrogen or a hydrocarbon residue which may optionally be substituted; R 4 represents (1) a hydrocarbon residue which is substituted by an optionally protected amino group or (2) an alkenyl group; or R 3 and R 4 may be combined with the adjacent nitrogen atom to form a heterocyclic group containing at least two hetero atoms, or a salt thereof.The compound or a salt thereof of the present invention inhibits thiol proteases such as cathepsin L and B and serves well as a prophylactic/therapeutic agent for bone diseases such as osteoporosis.