114963-62-1 Usage
Description
(R)-1-amino-3-hydroxybutane, also known as D-threonine, is an organic compound classified as a non-proteinogenic amino acid with a molecular formula of C4H10NO3. It is not typically incorporated into proteins during translation but serves as a crucial intermediate in the biosynthesis of various compounds, such as antibiotics and peptide-based drugs. D-threonine is also utilized in the production of chiral catalysts and as a building block in organic synthesis. Its potential applications extend to the fields of medicine and biotechnology, particularly in the development of novel therapeutics and pharmaceuticals.
Uses
Used in Pharmaceutical Industry:
(R)-1-amino-3-hydroxybutane is used as an intermediate for the synthesis of various antibiotics and peptide-based drugs, contributing to the development of new therapeutic agents.
Used in Catalyst Production:
(R)-1-amino-3-hydroxybutane is used as a building block in the production of chiral catalysts, which are essential in the pharmaceutical and chemical industries for enantioselective reactions.
Used in Organic Synthesis:
(R)-1-amino-3-hydroxybutane is used as a building block in organic synthesis, enabling the creation of complex molecules with specific properties for various applications.
Used in Medicine and Biotechnology:
(R)-1-amino-3-hydroxybutane is used as a research compound for exploring its potential in the development of novel therapeutics and pharmaceuticals, particularly in the context of medicine and biotechnology.
Check Digit Verification of cas no
The CAS Registry Mumber 114963-62-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,9,6 and 3 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 114963-62:
(8*1)+(7*1)+(6*4)+(5*9)+(4*6)+(3*3)+(2*6)+(1*2)=131
131 % 10 = 1
So 114963-62-1 is a valid CAS Registry Number.
114963-62-1Relevant articles and documents
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Robinson,Suginome
, p. 298,302 (1932)
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PROTECTION OF PRIMARY AND SECONDARY AMINES IN THE HYDROBORATION REACTION
Dicko, A.,Montury, M.,Baboulene, M.
, p. 6041 - 6044 (1987)
Trimethylsilyl groups are efficient to protect the N-H bonds of olefinic amines in the hydroboration reaction with BMS; deprotection is easily run with methanol and affords aminoorganoboranes which can be used without any oxydation.
Amine-directed hydroboration: Scope and limitations
Scheideman, Matthew,Wang, Guoqiang,Vedejs, Edwin
supporting information; experimental part, p. 8669 - 8676 (2009/02/03)
Iodine activation induces intramolecular hydroboration of homoallylic and bis-homoallylic amine boranes with good to excellent control of regiochemistry compared to control experiments using excess THF?BH3. Deuterium labeling and other evidence confirm that the iodine-induced hydroboration reaction of homoallylic amine boranes occurs via an intramolecular mechanism equivalent to the classical 4-center process and without competing retro-hydroboration. Longer carbon chain tethers result in lower regioselectivity, whereas the shorter tether in allylic amines results in a switch to dominant intermolecular hydroboration. Regioselectivity in THF?BH3 control experiments is higher for the allylic amine boranes compared to the iodine activation experiments, whereas the reverse is true for homoallylic amine borane activation.
