1149660-53-6

Basic information

• Product Name: 4-(5-Nitro-2-trifluoromethoxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester
• Synonyms: 4-(5-Nitro-2-trifluoromethoxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester
• CAS NO: 1149660-53-6
• Molecular Weight: 391.347
• Mol File: 1149660-53-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(5-Nitro-2-trifluoromethoxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(5-Nitro-2-trifluoromethoxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester(1149660-53-6)
• EPA Substance Registry System: 4-(5-Nitro-2-trifluoromethoxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester(1149660-53-6)

Safety Data

• Hazardous Substances Data: 1149660-53-6(Hazardous Substances Data)

Upstream product

• 200958-40-3 2-bromo-4-nitro-1-(trifluoromethoxy)benzene 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 

Downstream Products

• 1149660-55-8 4-(5-Amino-2-trifluoromethoxy-phenyl)-piperazine-1-carboxylic Acid tert-butyl Ester 

Relevant articles and documents

BENZENESULFONANILIDE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR

The present invention relates to novel benzenesulfonanilide compounds of the formulae I and I′ and physiologically tolerated acid addition salts and the N-oxides thereof. The compounds possess valuable therapeutic properties and are particularly suitable, for treating diseases that respond to modulation of the serotonin 5-HT6 receptor. wherein R1 is hydrogen or methyl R2 is hydrogen or methyl R3 hydrogen, fluorine C1-C2 alkoxy or fluorinated C1-C2 alkoxy; R4 is hydrogen, C1-C4 alkyl or fluorinated C1-C4 alkyl; R5 is hydrogen, fluorine, C1-C2 alkyl fluorinated C1-C2 alkyl C1-C2 alkoxy or fluorinated C1-C2 alkoxy; and R6 is hydrogen, fluorine or chlorine.