1150618-50-0

Basic information

• Product Name: 1-isopropyl-1H-imidazole-4-carboxylic acid methyl ester
• CAS NO: 1150618-50-0
• Molecular Weight: 168.195
• Mol File: 1150618-50-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 289.6±13.0 °C(Predicted)
• Density: 1.12±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 1-isopropyl-1H-imidazole-4-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-isopropyl-1H-imidazole-4-carboxylic acid methyl ester(1150618-50-0)
• EPA Substance Registry System: 1-isopropyl-1H-imidazole-4-carboxylic acid methyl ester(1150618-50-0)

Safety Data

• Hazardous Substances Data: 1150618-50-0(Hazardous Substances Data)

Usage

General Description

1-isopropyl-1H-imidazole-4-carboxylic acid methyl ester is a chemical compound with the molecular formula C9H12N2O2. It is a methyl ester derivative of imidazole-4-carboxylic acid, containing an isopropyl group attached to the nitrogen atom of the imidazole ring. 1-isopropyl-1H-imidazole-4-carboxylic acid methyl ester is commonly used as an intermediate for the synthesis of pharmaceuticals and agrochemicals. It is also used in the production of dyes, pigments, and other organic compounds. The methyl ester group of this compound makes it more stable and easier to handle in chemical reactions, and it can be further modified into various derivatives for specific applications in the chemical and pharmaceutical industries.

Upstream product

• 72130-98-4 (Z)-1-(dimethylamino)-3-methoxy-N-methylidyne-3-oxoprop-1-en-2-aminium 
• 75-31-0 isopropylamine 
• 39687-95-1 isocyanoacetic acid methyl ester 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 75-30-9 2-iodo-propane 
• 17325-26-7 Methyl imidazole-4-carboxylate 

Downstream Products

• 917364-12-6 1-isopropyl-1H-imidazole-4-carboxylic acid 
• 1355346-40-5 1-[4-(6,7-dimethoxyquinolin-4-yloxy)phenyl]-3-(1-isopropyl-1H-imidazol-4-yl)urea 
• 1620582-86-6 1-(3-chloro-2-fluoro-phenyl)-6-(4-chloro-2-methyl-phenyl)-7-isopropyl-8-(2-methoxy-phenyl)-1,3,6,7-tetrahydro-purin-2-one 
• 1620583-20-1 1-isopropyl-2-(2-methoxy-phenyl)-1H-imidazole-4-carboxylic acid methyl ester 
• 1620583-18-7 methyl 5-((4-chloro-2-methylphenyl)(methylsulfonyloxy)methyl)-1-isopropyl-2-(2-methoxyphenyl)-1H-imidazole-4-carboxylate 
• 1448870-40-3 5-[(3-chloro-2-fluoro-phenylamino)-(4-chloro-2-methyl-phenyl)methyl]-1-isopropyl-2-(2-methoxy-phenyl)-1H-imidazole-4-carboxylic acid methyl ester 
• 1620583-17-6 lithium 5-[(3-chloro-2-fluoro-phenylamino)-(4-chloro-2-methyl-phenyl)methyl]-1-isopropyl-2-(2-methoxy-phenyl)-1H-imidazole-4-carboxylate 

Relevant articles and documents

PYRROLIDINE AMIDE COMPOUNDS AS HISTONE DEMETHYLASE INHIBITORS

The present invention relates to compounds of formula (I) useful as inhibitors of one or more histone demethylses, such as KDM5. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and the compounds for use in methods for the treatment of various disorders. Formula (I): or a salt thereof, wherein: A is selected from the group consisting of:

NITROGENATED AROMATIC HETEROCYCLIC RING DERIVATIVE

The present invention provides a nitrogen-containing aromatic heterocyclic derivative represented by formula (I): [wherein W represents CR3 (wherein R3 represents a hydrogen atom or the like) or the like, R4 represents a hydrogen atom or the like, R5 represents a hydrogen atom or the like, R9 represents substituted imidazolyl, R12 and R13 may be the same or different, each represent a hydrogen atom or the like, R22 and R23 may be the same or different, each represent a hydrogen atom or the like, R24 represents a hydrogen atom or the like, Y represents C-R25 (wherein R25 represents a hydrogen atom or the like) or the like] or a pharmaceutically acceptable salt thereof and a FGFR inhibitor comprising, as an active ingredient, the nitrogen-containing aromatic heterocyclic derivative or the pharmaceutically acceptable salt thereof, or the like.