1152493-76-9

Basic information

• Product Name: 2-(3-phenoxyphenyl)benzoxazole
• Synonyms: 2-(3-phenoxyphenyl)benzoxazole
• CAS NO: 1152493-76-9
• Molecular Weight: 287.318
• Mol File: 1152493-76-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(3-phenoxyphenyl)benzoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-phenoxyphenyl)benzoxazole(1152493-76-9)
• EPA Substance Registry System: 2-(3-phenoxyphenyl)benzoxazole(1152493-76-9)

Safety Data

• Hazardous Substances Data: 1152493-76-9(Hazardous Substances Data)

Upstream product

• 50789-45-2 3-phenoxybenzonitrile 
• 51-19-4 2-aminophenol hydrochloride 
• 228423-11-8 3-phenoxy-N-phenylbenzamide 

Relevant articles and documents

Synthesis of 2-(3-phenoxyphenyl)-substituted benzoxazoles, based on nitriles containing the diphenyl oxide fragment

A method is proposed for the preparation of 2-(3-phenoxyphenyl)-substituted benzoxazoles, which are of interest as structural blocks for the synthesis of compounds possessing potential biological activity.

Copper-catalyzed synthesis of benzoxazoles via a regioselective C-H functionalization/C-O bond formation under an air atmosphere

(Chemical Equation Presented) An efficient method for the synthesis of functionalized benzoxazoles is described that involves a copper(II)-catalyzed regioselective C-H functionalization/C-O bond formation protocol. The use of dichlorobenzene as a solvent at 160°C allows the use of air as the terminal oxidant in the catalytic synthesis of benzoxazoles in a process that has high functional group tolerance. The presence of a directing group at the meta position markedly improves the reaction efficacy and a variety of 7-substituted benzoxazoles are selectively produced under mild reaction conditions. The mechanism of the reaction is also discussed in this report.