116-45-0

Basic information

• Product Name: 4-amino-N-(5-bromo-4,6-dimethyl-2-pyrimidinyl)benzenesulphonamide
• Synonyms: 4-amino-N-(5-bromo-4,6-dimethyl-2-pyrimidinyl)benzenesulphonamide;Sulfabromomethazine;4-Amino-N-(5-bromo-4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide;4-amino-N-(5-bromo-4,6-dimethyl-pyrimidin-2-yl)benzenesulfonamide;4-amino-N-(5-bromo-4,6-dimethylpyrimidin-2-yl)benzenesulfonamide;4-azanyl-N-(5-bromo-4,6-dimethyl-pyrimidin-2-yl)benzenesulfonamide;Sulfabrom
• CAS NO: 116-45-0
• Molecular Formula: C₁₂H₁₃BrN₄O₂S
• Molecular Weight: 357.22622
• EINECS: 204-142-6
• Mol File: 116-45-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: approximate 246℃ (dec.)
• Boiling Point: 568.3±60.0 °C(Predicted)
• Appearance: /
• Density: 1.653±0.06 g/cm3(Predicted)
• PKA: 7.16±0.10(Predicted)
• CAS DataBase Reference: 4-amino-N-(5-bromo-4,6-dimethyl-2-pyrimidinyl)benzenesulphonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-N-(5-bromo-4,6-dimethyl-2-pyrimidinyl)benzenesulphonamide(116-45-0)
• EPA Substance Registry System: 4-amino-N-(5-bromo-4,6-dimethyl-2-pyrimidinyl)benzenesulphonamide(116-45-0)

Safety Data

• Hazardous Substances Data: 116-45-0(Hazardous Substances Data)

Usage

Description

4-amino-N-(5-bromo-4,6-dimethyl-2-pyrimidinyl)benzenesulphonamide is a chemical compound with the molecular formula C12H13BrN4O2S. It is a derivative of sulfonamide, a class of antimicrobial agents, and features a 5-bromo-4,6-dimethyl-2-pyrimidinyl group attached to a benzene ring through an amide linkage. 4-amino-N-(5-bromo-4,6-dimethyl-2-pyrimidinyl)benzenesulphonamide is characterized by its crystalline structure and is soluble in alkaline solutions, with a decomposition temperature range of 250-252°C.

Uses

Used in Pharmaceutical Industry:
4-amino-N-(5-bromo-4,6-dimethyl-2-pyrimidinyl)benzenesulphonamide is used as a pharmaceutical intermediate for the synthesis of various drugs, particularly in the development of sulfonamide-based antimicrobial agents. Its unique structure allows for potential modifications and improvements in drug efficacy and selectivity.
Used in Veterinary Medicine:
In the veterinary field, 4-amino-N-(5-bromo-4,6-dimethyl-2-pyrimidinyl)benzenesulphonamide is used as a key component in the formulation of veterinary antibacterial drugs, such as sulfabromomethazine. This drug is effective in treating bacterial infections in animals and helps maintain their overall health.
Used as a Food Additive:
4-amino-N-(5-bromo-4,6-dimethyl-2-pyrimidinyl)benzenesulphonamide also finds application as a food additive, where it may serve various purposes, such as preserving food quality, enhancing flavor, or improving texture. Its use in this industry is subject to strict regulations and safety standards to ensure consumer health and well-being.

Safety Profile

When heated to decomposition it emits acrid smoke and irritating fumes.

Upstream product

• 4214-57-7 2-amino-5-bromo-4,6-dimethylpyrimidine 
• 121-60-8 p-acetylaminobenzenesulfonyl chloride 

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