116053-25-9

Basic information

• Product Name: 4-(Tetrahydro-pyran-2-yloxy)-but-2-ynoic acid
• Synonyms: 4-(Tetrahydro-pyran-2-yloxy)-but-2-ynoic acid
• CAS NO: 116053-25-9
• Molecular Weight: 184.192
• Mol File: 116053-25-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(Tetrahydro-pyran-2-yloxy)-but-2-ynoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(Tetrahydro-pyran-2-yloxy)-but-2-ynoic acid(116053-25-9)
• EPA Substance Registry System: 4-(Tetrahydro-pyran-2-yloxy)-but-2-ynoic acid(116053-25-9)

Safety Data

• Hazardous Substances Data: 116053-25-9(Hazardous Substances Data)

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 7218-52-2 4-hydroxy-2-butynoic acid 

Downstream Products

• 7218-52-2 4-hydroxy-2-butynoic acid 

Relevant articles and documents

Ruthenium-catalyzed asymmetric [2 + 2] cycloadditions between chiral acyl camphorsultam-substituted alkynes and bicyclic alkenes

Ruthenium-catalyzed asymmetric [2 + 2] cycloadditions between chiral acyl camphorsultam-functionalized alkynes and bicyclic alkenes were examined, providing adducts with complete exo stereoselectivity in good overall yield and enantioselectivity (up to 99% and 166:1, respectively), as well as appreciable diastereoselectivity (up to 163:1). The diastereoselectivity showed dependence on the solvent and temperature, as well as on the substitution pattern of the reacting alkyne and bicyclic alkene components. In general, higher diastereoselectivities were observed for reactions conducted in ethereal solvents and at lower temperatures between N-propynoyl camphorsultams and bicyclic alkenes.