116055-27-7Relevant articles and documents
A simple method for the synthesis of 1,3-diaminopropan-2-ols derivatives and their ex vivo relaxant activity on isolated rat tracheal rings
López, Fabiola I.,de la Cruz, Fabiola N.,López, Julio,Martínez, J. Merced,Alcaraz, Yolanda,Delgado, Francisco,Sánchez-Recillas, Amanda,Estrada-Soto, Samuel,Vázquez, Miguel A.
, p. 1325 - 1335 (2017/05/04)
Abstract: A mild and eco-friendly method has been developed for the synthesis of a series of 1,3-diaminopropan-2-ols 8a–n. The epoxide of epichlorohydrin undergoes ring-opening with amines using MgSO4 or mixed metal oxides catalysts under mild