1160918-88-6

Basic information

• Product Name: 4-[(4-methyl-1H-indol-5-yl)amino]-5-{(E)-2-[3-(2-pyrrolidin-1-ylethoxy)phenyl]vinyl}nicotinonitrile
• Synonyms: 4-[(4-methyl-1H-indol-5-yl)amino]-5-{(E)-2-[3-(2-pyrrolidin-1-ylethoxy)phenyl]vinyl}nicotinonitrile
• CAS NO: 1160918-88-6
• Molecular Weight: 463.582
• Mol File: 1160918-88-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-[(4-methyl-1H-indol-5-yl)amino]-5-{(E)-2-[3-(2-pyrrolidin-1-ylethoxy)phenyl]vinyl}nicotinonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(4-methyl-1H-indol-5-yl)amino]-5-{(E)-2-[3-(2-pyrrolidin-1-ylethoxy)phenyl]vinyl}nicotinonitrile(1160918-88-6)
• EPA Substance Registry System: 4-[(4-methyl-1H-indol-5-yl)amino]-5-{(E)-2-[3-(2-pyrrolidin-1-ylethoxy)phenyl]vinyl}nicotinonitrile(1160918-88-6)

Safety Data

• Hazardous Substances Data: 1160918-88-6(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 
• 730978-54-8 3-bromophenyl 2-chloroethyl ether 
• 1160918-11-5 4-[(4-methyl-1H-indol-5-yl)amino]-5-vinylnicotinonitrile 
• 1160918-80-8 5-{(E)-2-[3-(2-chloroethoxy)phenyl]vinyl}-4-[(4-methyl-1H-indol-5-yl)amino]nicotinonitrile 

Relevant articles and documents

5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS

Described herein are compounds of formula I: wherein G is and pharmaceutically acceptable salts thereof, wherein J, X, R1, R2, R11, R12' and p are as defined herein. Also provided herein are methods of making the compounds of formula I, and methods of using these compounds for inhibiting or treating a pathological condition or disorder linked to or mediated by a protein kinase in a mammal.