116690-83-6Relevant articles and documents
The Preparation of Quinolines and Related Fused-Ring Heterocycles from the Dianions of Benzoylacetone, Certain Cyclic Ketone Oximes, or Certain Substituted Hydrazones
Mack, H. Michael,Davis, Everette A.,Kadkhodayan, Babak,Taylor, Richard A.,Duncan, Dean C.,Beam, Charles F.
, p. 1733 - 1740 (2007/10/02)
C(α),O-Dilithiooximes, C(α),N-dilithiobenzoylhydrazones, or C(α),N-dilithiocarboalkoxyhydrazones were prepared in an excess of lithium diisopropylamide (LDA) and condensed with 2-aminobenzophenones, or isatoic anhydrides to give intermediates that were treated with aqueous acid, which caused their hydrolysis, cyclodehydration and/or linear dehydration to give products which were substituted quinolines or related fused-ring heterocycles (e.g., cycloheptaquinolines).Dilithiobenzoylacetone was condensed with 2-aminobenzophenones, which was followed by acid cyclodehydration to substituted 2-phenacylquinolines.