1167055-73-3 Usage
General Description
4-Oxazolecarboxylic acid, 2-bromo- is a chemical compound with the molecular formula C5H3BrNO3. It is an oxazole derivative with a bromo substituent at the 2-position. 4-Oxazolecarboxylicacid, 2-broMo- is used in the synthesis of pharmaceuticals and agrochemicals. It is also used as a building block in organic synthesis. Additionally, it has potential applications in medicinal chemistry and drug discovery. This chemical compound has attracted attention for its interesting biological activities and potential use as a therapeutic agent.
Check Digit Verification of cas no
The CAS Registry Mumber 1167055-73-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,6,7,0,5 and 5 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1167055-73:
(9*1)+(8*1)+(7*6)+(6*7)+(5*0)+(4*5)+(3*5)+(2*7)+(1*3)=153
153 % 10 = 3
So 1167055-73-3 is a valid CAS Registry Number.
1167055-73-3Relevant articles and documents
Widely Exploited, Yet Unreported: Regiocontrolled Synthesis and the Suzuki–Miyaura Reactions of Bromooxazole Building Blocks
Solomin, Vitalii V.,Radchenko, Dmytro S.,Slobodyanyuk, Evgeniy Y.,Geraschenko, Oleksandr V.,Vashchenko, Bohdan V.,Grygorenko, Oleksandr O.
, p. 2884 - 2898 (2019/03/07)
An approach to synthesis of 2-, 4-, and 5-bromooxazoles is described. The method was optimized, and its scope was extended to all three isomeric parents, as well as various alkyl- and aryl-substituted bromooxazoles. It was found that direct regiocontrolled lithiation followed by reaction with electrophilic bromine source was common for all substrates and led exclusively to the target substituted 2-, 4- and 5-bromooxazoles on multigram scale. The utility of the multipurpose building blocks obtained in this work was demonstrated in the Suzuki–Miyaura cross-coupling reaction under parallel synthesis conditions.
