116792-06-4

Basic information

• Product Name: 3-chloro-8-methoxy-11H-indolo[3,2-c]quinoline
• Synonyms: 3-Chloro-8-methoxy-11H-indolo[3,2-c]quinoline
• CAS NO: 116792-06-4
• Molecular Formula: C₁₆H₁₁ClN₂O
• Molecular Weight: 282.7243
• Mol File: 116792-06-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 528.3°C at 760 mmHg
• Flash Point: 273.3°C
• Density: 1.418g/cm³
• Vapor Pressure: 1.02E-10mmHg at 25°C
• Refractive Index: 1.783
• CAS DataBase Reference: 3-chloro-8-methoxy-11H-indolo[3,2-c]quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-8-methoxy-11H-indolo[3,2-c]quinoline(116792-06-4)
• EPA Substance Registry System: 3-chloro-8-methoxy-11H-indolo[3,2-c]quinoline(116792-06-4)

Safety Data

• Hazardous Substances Data: 116792-06-4(Hazardous Substances Data)

Upstream product

• 21617-15-2 7-chloro-1,2,3,4-tetrahydroquinolin-4-one 
• 19501-58-7 4-methoxyphenylhydrazine hydrochloride 
• 42313-47-3 methyl N-(3-chlorophenyl)-β-alaninate 
• 66820-85-7 7-chloro-1-(toluene-4-sulfonyl)-2,3-dihydro-1H-quinolin-4-one 
• 66737-56-2 N-(3-chlorophenyl)-N-<(4-methylphenyl)sulfonyl>-β-alanine 
• 155250-02-5 methyl N-(3-chlorophenyl)-N-<(4-methylphenyl)sulfonyl>-β-alaninate 
• 108-42-9 3-chloro-aniline 

Relevant articles and documents

Structure-activity relationships of antimalarial indoloquinolines

Structure-activity relationships have been ascertained and chemical metodology developed for a series of antimalarial 3-chloroindoloquinoline-5-oxides.The basic side chain as well as the ring N-oxide are critical for antimalarial activity as is a bromine or chlorine in position 3.Substitution at positions 7,8,9,10 in not essential, although the most potent analog in our studies was the 8-nitro compound 4vv. indoloquinolines / antimalarial agents