117428-51-0Relevant articles and documents
New Manufacturing Route to Picoxystrobin
Chen, Yu,Lu, Huan,Dai, Hui,Yu, Wansheng,Pan, Xianhua
, p. 195 - 198 (2016)
A new and efficient manufacturing technology is disclosed in the present work for the preparation of picoxystrobin in which all of the intermediates can be used directly in the next step of the process without purification.
A (E) - 2 - (the 2 [...] -chloromethyl) phenyl-3-methoxy methyl acrylate preparation method
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Paragraph 0031; 0032, (2016/11/14)
The invention discloses a novel preparation method of (E)-2-(2'-chloromethyl) phenyl-3-methoxy methyl acrylate. The preparation method comprises the following steps: with 3-isochromanone as a starting material, under actions of trimethyl orthoformate and glacial acetic acid, performing condensation reaction to obtain an intermediate, and reacting the intermediate with thionyl chloride and methanol in sequence to obtain the (E)-2-(2'-chloromethyl) phenyl-3-methoxy methyl acrylate. According to the preparation method, the process is relatively simple, the raw materials are easy to obtain, the cost is low, the solid, liquid and gas wastes are few, and the content and yield of the target product are relatively high, and the method is suitable for industrial production.
PROCESSES FOR PRODUCING ACRYLIC ACID DERIVATIVE
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, (2008/06/13)
Processes for producing a compound (1) represented by formula (1), which includes an acrylic acid derivative and is useful as an agricultural chemical or medicine. One of the processes comprises the step of formylating a compound (3) (step (1)) and the step of converting the OH of the resultant compound (2) into OR" (step (2)). The step (1) comprises reacting a formic or orthoformic ester in the presence of a Lewis acid and a base. The step (2) comprises [1] reacting the compound (2) with R" OH or with R" OH and CH(OR")3under acidic conditions or [2] using a phase-transfer catalyst in a two-phase system and regulating the base and the concentration thereof to stereoselectively synthesize the target compound. In another process, the compound (1) is efficiently produced without isolating the compound (2). In still another process, the compound (1) is directly produced without via the compound (2).