117832-13-0

Basic information

• Product Name: 2,5-DIMETHYL-4-IODOANILINE
• Synonyms: 2,5-DIMETHYL-4-IODOANILINE;CHEMBRDG-BB 9071881;ASISCHEM Y88810;(4-iodo-2,5-dimethylphenyl)amine(SALTDATA: FREE);(4-iodo-2,5-dimethylphenyl)amine;4-iodo-2,5-dimethylaniline
• CAS NO: 117832-13-0
• Molecular Formula: C₈H₁₀IN
• Molecular Weight: 247.08
• Mol File: 117832-13-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 290.7 °C at 760 mmHg
• Flash Point: 129.6 °C
• Appearance: /
• Density: 1.688 g/cm³
• Vapor Pressure: 0.00203mmHg at 25°C
• Refractive Index: 1.644
• CAS DataBase Reference: 2,5-DIMETHYL-4-IODOANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DIMETHYL-4-IODOANILINE(117832-13-0)
• EPA Substance Registry System: 2,5-DIMETHYL-4-IODOANILINE(117832-13-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 117832-13-0(Hazardous Substances Data)

Usage

General Description

2,5-DIMETHYL-4-IODOANILINE is a chemical compound with the molecular formula C8H10IN. It is a member of the aniline family and is characterized by its two methyl groups and one iodine atom attached to the central benzene ring. 2,5-DIMETHYL-4-IODOANILINE is commonly used in the synthesis of various pharmaceuticals, dyes, and agrochemicals. It is also utilized as an intermediate in the production of other organic compounds. 2,5-DIMETHYL-4-IODOANILINE is known to be potentially hazardous and should be handled with caution, as exposure to this chemical can cause skin and eye irritation, as well as respiratory and digestive tract issues.

InChI:InChI=1/C8H10IN/c1-5-4-8(10)6(2)3-7(5)9/h3-4H,10H2,1-2H3

Upstream product

• 6311-51-9 1-iodo-2,5-dimethyl-4-nitro-benzene 
• 95-78-3 2,5-Dimethylaniline 

Downstream Products

• 1124-08-9 2,5-diiodo-p-xylene 
• 953394-04-2 dibenzyl-(4-iodo-2,5-dimethylphenyl)amine hydrochloride 
• 953394-14-4 N-(4-iodo-2,5-dimethylphenyl)acrylamide 
• 276678-49-0 2,5-dimethyl-4-(2-methoxycarbonyl-ethyl-amino)-1-iodo-benzene 
• 276678-52-5 2,5-dimethyl-4-iodo-N-isopropyl-aniline 
• 953394-03-1 dibenzyl-(4-iodo-2,5-dimethylphenyl)amine 
• 1374427-93-6 2,5-dimethyl-4-(3,3-dimethyl-1-butynyl)aniline 
• 1374427-95-8 2,5-dimethyl-4-(2-trimethylsilyl-1-ethynyl)aniline 
• 1374426-32-0 N,N-dimethyl-N'-[2,5-dimethyl-4-(3,3-dimethyl-1-butynyl)phenyl]formamidine 
• 1374426-39-7 N,N-dimethyl-N'-[2,5-dimethyl-4-(2-trimethylsilyl-1-ethynyl)phenyl]formamidine 
• 1374427-03-8 N-ethyl-N-methyl-N′-[2,5-dimethyl-4-(2-trimethylsilyl-1-ethynyl)phenyl]formamidine 
• 1374427-45-8 N-ethyl-N-methyl-N′-[2,5-dimethyl-4-(2-trimethylsilyl-1-ethynyl)phenyl]formamidine hydrochloride 
• 1374427-66-3 N-ethyl-N-methyl-N'-[2,5-dimethyl-4-(2-trimethylsilyl-1-ethynyl)phenyl]formamidine (+)-camphorsulfonate 
• 954136-51-7 dibenzyl-(4-[1,3]dioxolan-2-yl-2,5-dimethyl-phenyl)amine 

Relevant articles and documents

Regioselective iodination of aryl amines using 1,4-dibenzyl-1,4-diazoniabicyclo [2.2.2] octane dichloroiodate in solution and under solvent-free conditions

1,4-Dibenzyl-1,4-diazoniabicyclo[2.2.2]octane dichloroiodate is an efficient and regioselective reagent for iodination of aryl amines. A wide variety of aryl amines in reaction with this reagent afforded regioselectively iodinated products. The iodination reaction can be carried out in solution or under solvent-free condition at room temperature.

Iodination of anilines and phenols with 18-crown-6 supported ICl 2-

A highly crystalline iodinating reagent, {[K·18-C-6]ICl 2}n, was synthesized in high yield (93%). The trihalide is supported by an 18-crown-6 macrocycle and forms a coordination polymer in the solid state. This reagent iodinates anilines and phenols efficiently under mild conditions. Controlled mono-iodination with anilines was easily achieved while poly-iodination was observed with phenols.

Dialkylphenyl compounds having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity

This invention relates to compounds of formula I: wherein R1 and R2 are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The invention also relates to pharmaceutical compositions and combinations comprising such compounds, processes and intermediates for preparing such compounds, and methods of using such compound to, for example, treat pulmonary disorders, such as chronic obstructive pulmonary disease and asthma.