1178859-01-2

Basic information

• Product Name: 2'-Chloro-2,5-difluoro-4-methoxybenzophenone
• Synonyms: 2'-Chloro-2,5-difluoro-4-methoxybenzophenone
• CAS NO: 1178859-01-2
• Molecular Weight: 282.674
• Mol File: 1178859-01-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2'-Chloro-2,5-difluoro-4-methoxybenzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-Chloro-2,5-difluoro-4-methoxybenzophenone(1178859-01-2)
• EPA Substance Registry System: 2'-Chloro-2,5-difluoro-4-methoxybenzophenone(1178859-01-2)

Safety Data

• Hazardous Substances Data: 1178859-01-2(Hazardous Substances Data)

Upstream product

• 609-65-4 o-chlorobenzoyl chloride 
• 134364-69-5 2.3-difluoroanisole 

Downstream Products

• 1178859-02-3 2-(Benzylamino)-2'-chloro-5-fluoro-4-methoxybenzophenone 
• 1178859-05-6 2-(Allylamino)-2'chloro-5-fluoro-4-methoxybenzophenone 
• 1178859-04-5 2-(N,N-Diallylamino)-2'-(2-chlorobenzoyl)-4'-fluoro-5'-methoxyacetanilide 

Relevant articles and documents

Process for preparing pyrazole functionalized benzodiazepinones

The present invention provides innovative strategies for synthesizing pyrazole ring-functionalized benzodiazepinones. Alternative intermediates and high conversion strategies for forming alpha-aminobenzophenone intermediates involve a combination of aromatic acylation, displacement of electronegative leaving groups with amine, and then N-displacement strategies to produce the desired alpha-aminobenzophenone with primary amine functionality. Reaction strategies are then provided for converting alpha-aminobenzophenones to alpha-aminoamidobenzophenone intermediates with high yield and convenient reaction strategies. These alpha-aminoamidobenzophenone intermediates are then converted into benzodiazepinones. These benzodiazepinones are then converted to pyrazole ring functionalized benzodiazepinones through a series of innovative intermediates and/or reaction strategies.