117992-54-8Relevant articles and documents
Sulfone derivatives enter the cytoplasm of Candida albicans sessile cells
Arroyo-Córdoba, Ismael J.,Kobiela, Tomasz,Koronkiewicz, Miros?awa,Kuryk, ?ukasz,Ma?gorzata, Gizińska,Michalina, Kazek,Ochal, Zbigniew,Pe?a-Cabrera, Eduardo,Sobiepanek, Anna,Staniszewska, Monika,Wieczorek, Magdalena
, (2020)
Since our study showed that sulfone derivatives’ action mode creates a lesser risk of inducing widespread resistance among Candida spp., we continued verifying sulfones’ antifungal activity using the following newly synthesized derivatives: bromodichlorom
A simple and efficient synthesis of trihalomethyl and dihalonitromethyl aryl sulfones
Borys, Krzysztof M.,Korzynski, MacIej D.,Ochal, Zbigniew
, p. 6606 - 6610,5 (2012/12/12)
A method for the preparation of aryl trihalomethyl sulfones - active biocidal agents - with identical or different halogens is presented. The synthesis is based on the reaction of aryl methyl, aryl halomethyl, or aryl nitromethyl sulfones with sodium hypohalite. The method is simple in implementation, does not necessarily require the use of organic solvents, and selectively affords the products in good to excellent yields. Notably, it allows the preparation of the hitherto unknown phenyl trihalomethyl sulfone with three different halogens: fluorine, chlorine, and bromine.
