118041-50-2Relevant articles and documents
Studies on the constituents of Actinostemma lobatum MAXIM. IV. Structures of Lobatosides C, D and H, the dicrotalic acid esters of bayogenin bisdesmosides isolated from the herb.
Fujioka, Toshihiro,Masayo, Iwamoto,Iwase, Yukiko,Hachiyama, Shizuko,Okabe, Hikaru,et. al
, p. 1770 - 1775 (2007/10/02)
Eight bayogenin glycosides, lobatosides A-H, were isolated from the herb of Actinostemma lobatum MAXIM.(Curcurbitaceae).The isolation of lobatosides A-H and the structures of lobatosides A, C, D and H are described.Lobatoside A is 3-O-2)-β-D-glucopyranosyl>bayogenin (2β,3β,23-trihydroxyolean-12-en-28-oic acid).Lobatosides C, D and H are dicrotalic acid (3-hydroxy-3-methylglutaric acid) esters of the 28-2)-α-L-arabinopyranosyl>ester, 28-3)-αL-rhamnopyranosyl-(1->2)-α-L-arabinopyranosyl>ester and 28-3)-α-L-rhamnopyranosyl-(1->2)-α-L-arabinopyranosyl>ester of lobatoside A, respectively.Dicrotalic acid is linked at one end to the C4hydroxyl group of the α-L-arabinopyranosyl group in the C3-linked sugar moiety, and at the order end to the C4-hydroxyl group of the α-L-rhamnopyranosyl group in the ester-linked sugar moiety to form a macrocyclic structure ("cyclic bisdesmoside").Lobatoside H was proved to be identical with tubeimoside I isolated from the tuber of Bolbostemma paniculatum (MAXIM).FRANQUET(Cucurbitaceae).Keywords - Actinostemma lobatum; Cucurbitaceae; oleanane-type triterpene glycoside; bayogenin; 2β,3β,23-trihydroxyolean-12-en-28-oic acid; lobatoside;,tubeimoside I; cyclic bisdesmoside; dicrotalic acid; 3-hydroxy-3-methylglutaric acid.
