118259-88-4

Basic information

• Product Name: 5-CHLORO-2,3-DIHYDRO-2,2-DIMETHYL-1H-INDEN-1-ONE
• Synonyms: 5-CHLORO-2,3-DIHYDRO-2,2-DIMETHYL-1H-INDEN-1-ONE
• CAS NO: 118259-88-4
• Molecular Formula: C₁₁H₁₁ClO
• Molecular Weight: 194.66
• Mol File: 118259-88-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 289.8±29.0 °C(Predicted)
• Appearance: /
• Density: 1.176±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 5-CHLORO-2,3-DIHYDRO-2,2-DIMETHYL-1H-INDEN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLORO-2,3-DIHYDRO-2,2-DIMETHYL-1H-INDEN-1-ONE(118259-88-4)
• EPA Substance Registry System: 5-CHLORO-2,3-DIHYDRO-2,2-DIMETHYL-1H-INDEN-1-ONE(118259-88-4)

Safety Data

• Hazardous Substances Data: 118259-88-4(Hazardous Substances Data)

Upstream product

• 42348-86-7 5-chloro-1-indanone 
• 865-47-4 potassium tert-butylate 
• 75-65-0 tert-butyl alcohol 
• 74-88-4 methyl iodide 
• 1355254-01-1 C₁₄H₂₁ClOSi 
• 18713-58-1 1-(4-chlorophenyl)-2-methylpropan-1-one 

Downstream Products

• 118259-89-5 5-chloro-2,3-dihydro-2,2-dimethyl-1 H-inden-1-amine 

Relevant articles and documents

Enantioselective Synthesis of Indanes with a Quaternary Stereocenter via Diastereoselective C(sp3)-H Functionalization

A practical synthesis of enantioenriched indane derivatives with quaternary stereocenters was developed via sequential enantioselective reduction and C-H functionalization. Good to excellent enantioselectivity could be achieved by either the CuH-catalyzed asymmetric reduction or the Corey-Bakshi-Shibata (CBS) reduction of indanone derivatives. The subsequent diastereospecific and regioselective rhodium-catalyzed silylation of the methyl C-H bond led to indane derivatives with quaternary centers. This strategy was further applied in syntheses of (nor)illudalane and botryane sesquiterpenoids.

Synthesis of α-indanones via intramolecular direct arylation with cyclopropanol-derived homoenolates

A palladium-catalysed, tandem cyclopropanol rearrangement and direct arylation approach for the synthesis of 1-indanones is reported. The reaction is generally high yielding, uses oxygen as the terminal oxidant and tolerates a range of functional groups on the aryl ring.

1H-imidazole-5-carboxylic acid derivatives

A method of controlling weeds by applying thereto or to the locus thereof of an imidazole derivative of formula wherein, R1 is hydrogen or mercapto;, L is cyano or a radical of formula X is 1-indanyl, 1-tetrahydronaphthalenyl, 5-benzocycloheptanyl, 4-tetr