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1184873-24-2

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1184873-24-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1184873-24-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,4,8,7 and 3 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1184873-24:
(9*1)+(8*1)+(7*8)+(6*4)+(5*8)+(4*7)+(3*3)+(2*2)+(1*4)=182
182 % 10 = 2
So 1184873-24-2 is a valid CAS Registry Number.

1184873-24-2Relevant articles and documents

Synthesis and investigations of double-pharmacophore ligands for treatment of chronic and neuropathic pain

Vardanyan, Ruben,Vijay, Gokhale,Nichol, Gary S.,Liu, Lu,Kumarasinghe, Isuru,Davis, Peg,Vanderah, Todd,Porreca, Frank,Lai, Josephine,Hruby, Victor J.

experimental part, p. 5044 - 5053 (2009/12/04)

Acids 9a-f as possible bivalent ligands designed as a structural combination of opioid μ-agonist (Fentanyl) and NSAID (Indomethacin) activities and produced compounds which were tested as analgesics. The obtained series of compounds exhibits low affinity and activity both at opioid receptors and as cyclooxygenase (COX) inhibitors. One explanation of the weak opioid activity could be stereochemical peculiarities of these bivalent compounds which differ significantly from the fentanyl skeleton. The absence of significant COX inhibitory properties could be explained by the required substitution of an acyl fragment in the indomethacin structure for 4-piperidyl.

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