1185094-00-1

Basic information

• Product Name: 5-Methoxy-4-methylpyridin-3-amine hydrochloride
• Synonyms: 5-Methoxy-4-methylpyridin-3-amine hydrochloride;3-Pyridinamine, 5-methoxy-4-methyl-, hydrochloride (1:1)
• CAS NO: 1185094-00-1
• Molecular Formula: C₇H₁₀N₂O*ClH
• Molecular Weight: 175
• Mol File: 1185094-00-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 5-Methoxy-4-methylpyridin-3-amine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methoxy-4-methylpyridin-3-amine hydrochloride(1185094-00-1)
• EPA Substance Registry System: 5-Methoxy-4-methylpyridin-3-amine hydrochloride(1185094-00-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 1185094-00-1(Hazardous Substances Data)

Usage

Description

5-Methoxy-4-methylpyridin-3-amine hydrochloride is a chemical compound with a molecular formula of C8H12N2OCl. It is a derivative of pyridine and amines, known for its potential therapeutic properties and commonly used in medical and pharmaceutical research.
Used in Pharmaceutical Research:
5-Methoxy-4-methylpyridin-3-amine hydrochloride is used as a research compound for investigating its potential therapeutic properties and applications in treating various health conditions.
Used in Drug Synthesis and Development:
5-Methoxy-4-methylpyridin-3-amine hydrochloride is used as a key intermediate in the synthesis and development of new drugs, particularly those targeting neurological disorders and cancer.
Used in Medical Applications:
5-Methoxy-4-methylpyridin-3-amine hydrochloride is used as a potential therapeutic agent for treating various health conditions, including neurological disorders and cancer, due to its potential therapeutic properties.
Used in Research and Development:
5-Methoxy-4-methylpyridin-3-amine hydrochloride is used as a research and development tool for exploring its potential applications in medicine and pharmaceuticals.
Used in Solubility and Stability Enhancement:
5-Methoxy-4-methylpyridin-3-amine hydrochloride is used in its hydrochloride salt form to improve its stability and solubility in water, which is beneficial for its application in research and development.

Upstream product

• 1045858-10-3 tert-butyl 5-methoxy-4-methylpyridin-3-ylcarbamate 
• 342603-10-5 tert-butyl 5-methoxypyridin-3-ylcarbamate 
• 64436-92-6 3-amino-5-methoxypyridine 
• 50720-12-2 3-bromo-5-methoxypyridine 

Downstream Products

• 77903-28-7 3-Amino-5-methoxy-4-methylpyridine 
• 1192255-92-7 (3-methoxy[1,5]naphthyridin-4-yl)methanol 
• 1056877-13-4 3-methoxy-1,5-naphthyridine-4-carbaldehyde 
• 1056877-14-5 3-hydroxy[1,5]naphthyridine-4-carbaldehyde 
• 1192256-10-2 3-descladinosyl-11,12-dideoxy-6-O-methyl-3-oxo-12,11-(oxycarbonyl-(1-((3-hydroxy-[1,5]naphthyridin-4-yl)-methyl)-azetidin-3-yl)-imino)-erythromycin A tosylate 

Relevant articles and documents

Process development of a novel azetidinyl ketolide antibiotic

Process development and the multikilogram synthesis of a novel azetidinyl ketolide antibiotic is described. Starting with clarithromycin, the eight-step synthesis features several telescoped operations and direct isolations, which results in a significant improvement in throughput and a major reduction in solvent usage and waste stream volume over the first scale-up campaign. Particular highlights of this effort include the development of an efficient synthesis of 3-hydroxy-1,5-naphthyridine-4-carbaldehyde via a Skraup process and engineering a robust final API synthesis. We also discovered a crystalline monotosylate salt that addressed significant formulation and degradation issues experienced when using the noncrystalline freebase.