1185251-08-4 Usage
Description
3-[(6-Acetyl-2-naphthalenyl)amino]alanine is a synthetic compound that serves as a key intermediate in the synthesis of fluorescent unnatural amino acids. It is characterized by its unique structure, which incorporates a naphthalene moiety and an acetylated amino group, allowing for the development of novel fluorescent probes and imaging agents.
Uses
Used in Fluorescent Probes and Imaging Agents:
3-[(6-Acetyl-2-naphthalenyl)amino]alanine is used as a building block for the synthesis of genetically encodable fluorescent unnatural amino acid L-3-(6-Acetylnaphthalen-2-ylamino)-2-aminopropanoic acid. This fluorescent amino acid can be incorporated into proteins, enabling researchers to study protein dynamics, interactions, and localization within living cells and organisms with high spatial and temporal resolution.
Used in Chemical Biology and Drug Discovery:
3-[(6-Acetyl-2-naphthalenyl)amino]alanine can be utilized in the development of chemical probes and tools for studying biological processes and pathways. Its unique fluorescent properties allow for the tracking and visualization of biomolecules, facilitating the discovery of novel drug targets and the optimization of therapeutic agents.
Used in Materials Science:
3-[(6-Acetyl-2-naphthalenyl)aMino]alanine's fluorescent properties can also be harnessed in the field of materials science, where it can be incorporated into various materials to create new types of sensors, optoelectronic devices, and other advanced materials with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 1185251-08-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,5,2,5 and 1 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1185251-08:
(9*1)+(8*1)+(7*8)+(6*5)+(5*2)+(4*5)+(3*1)+(2*0)+(1*8)=144
144 % 10 = 4
So 1185251-08-4 is a valid CAS Registry Number.
1185251-08-4Relevant articles and documents
Enantiospecific synthesis of genetically encodable fluorescent unnatural amino acid l-3-(6-acetylnaphthalen-2-ylamino)-2-aminopropanoic acid
Xiang, Zheng,Wang, Lei
, p. 6367 - 6371 (2011/10/02)
Fluorescent unnatural amino acids (UAAs), when genetically incorporated into proteins, can provide unique advantages for imaging biological processes in vivo. Synthesis of optically pure l-enantiomer of fluorescent UAAs is crucial for their effective application in live cells. An efficient six-step synthesis of l-3-(6-acetylnaphthalen-2-ylamino)-2-aminopropanoic acid (l-Anap), a genetically encodable and polarity-sensitive fluorescent UAA, has been developed. The synthesis takes advantage of a high-yield and enantiospecific Fukuyama-Mitsunobu reaction as the key transformation.
