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1186395-83-4

1186395-83-4

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1186395-83-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1186395-83-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,6,3,9 and 5 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1186395-83:
(9*1)+(8*1)+(7*8)+(6*6)+(5*3)+(4*9)+(3*5)+(2*8)+(1*3)=194
194 % 10 = 4
So 1186395-83-4 is a valid CAS Registry Number.

1186395-83-4Downstream Products

1186395-83-4Relevant articles and documents

Identification, synthesis and SAR of amino substituted pyrido[3,2b]pyrazinones as potent and selective PDE5 inhibitors

Owen, Dafydd R.,Walker, John K.,Jon Jacobsen,Freskos, John N.,Hughes, Robert O.,Brown, David L.,Bell, Andrew S.,Brown, David G.,Phillips, Christopher,Mischke, Brent V.,Molyneaux, John M.,Fobian, Yvette M.,Heasley, Steve E.,Moon, Joseph B.,Stallings, William C.,Joseph Rogier,Fox, David N.A.,Palmer, Michael J.,Ringer, Tracy,Rodriquez-Lens, Margarita,Cubbage, Jerry W.,Blevis-Bal, Radhika M.,Benson, Alan G.,Acker, Brad A.,Maddux, Todd M.,Tollefson, Michael B.,Bond, Brian R.,MacInnes, Alan,Yu, Yung

scheme or table, p. 4088 - 4091 (2010/04/02)

A new class of potent and selective PDE5 inhibitors is disclosed. Guided by X-ray crystallographic data, optimization of an HTS lead led to the discovery of a series of 2-aryl, (N8)-alkyl substituted-6-aminosubstituted pyrido[3,2b]pyrazinones which show p

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