1186423-68-6Relevant articles and documents
Synthesis of three 18F-labelled cyclooxygenase-2 (COX-2) inhibitors based on a pyrimidine scaffold
Tietz, Ole,Sharma, Sai Kiran,Kaur, Jatinder,Way, Jenilee,Marshall, Alison,Wuest, Melinda,Wuest, Frank
, p. 8052 - 8064 (2013/12/04)
Cyclooxygenase (COX) is the key enzyme within the complex conversion of arachidonic acid into prostaglandins (PGs). Inhibitors of this enzyme represent a particularly promising class of compounds for chemoprevention and cancer therapy. The experimental da