118671-39-9Relevant articles and documents
Visible light-induced one-pot synthesis of CF3/CF2-substituted cyclobutene derivatives
Ding, Aishun,Guo, Hao,Hu, Xiao,Xu, Dawen
supporting information, p. 7441 - 7444 (2021/08/03)
An efficient one-pot approach for the controllable synthesis of trifluoromethyl/gem-difluoromethylene substituted cyclobutene derivatives has been developed. The mechanism may involve visible light-induced [2+2]-cycloaddition of quinolinones with 1-bromo-1-trifluoromethylethene, followed by base-promoted dehydrobromination, [1,3]-H shift and further dehydrofluorination. A variety of CF3/CF2-substituted cyclobutenes that are currently difficult to obtain are afforded in good yields in this protocol, which may find its way into future fluorinated cyclobutene preparation.