1187448-81-2

Basic information

• Product Name: 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-2-(1,1-diMethylethyl)-5-Methyl-
• Synonyms: 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-2-(1,1-diMethylethyl)-5-Methyl-;2-(tert-butyl)-4-chloro-5-methyl-1H-pyrrolo[2,3-b]pyridine
• CAS NO: 1187448-81-2
• Molecular Formula: C₁₂H₁₅ClN₂
• Molecular Weight: 222.7139
• Mol File: 1187448-81-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-2-(1,1-diMethylethyl)-5-Methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-2-(1,1-diMethylethyl)-5-Methyl-(1187448-81-2)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-2-(1,1-diMethylethyl)-5-Methyl-(1187448-81-2)

Safety Data

• Hazardous Substances Data: 1187448-81-2(Hazardous Substances Data)

Usage

Structure

1H-Pyrrolo[2,3-b]pyridine core with a 4-chloro substituent on the pyridine ring, and 2 methyl groups on the pyrrolopyridine ring (one at position 5 and one as a 1,1-dimethylethyl group at position 2)

Uses

Commonly used in the pharmaceutical industry for its potential therapeutic applications, particularly in the treatment of various diseases and disorders

Biological activity

Known for its ability to modulate certain biological targets and has been studied for its potential antitumor and antiviral properties.

Upstream product

• 1187448-74-3 2-(1,1-dimethylethyl)-5-methyl-1H-pyrrolo[2,3-b]pyridine 
• 630-18-2 tert-butyl isocyanide 
• 591-22-0 3,5-Lutidine 
• 1187448-78-7 2-(1,1-dimethylethyl)-5-methyl-1H-pyrrolo[2,3-b]pyridine 7-oxide 

Downstream Products

• 1187448-98-1 1,1-dimethylethyl {2-[({4-[2-(1,1-dimethylethyl)-5-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl]phenyl}sulfonyl)amino]ethyl}carbamate 
• 1187448-48-1 4-[2-(1,1-dimethylethyl)-5-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl]-N-(1,1-dioxotetrahydro-2H-thiopyran-4-yl)benzenesulfonamide 

Relevant articles and documents

NOVEL COMPOUNDS

The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds according to formula (I) and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular IKK2 activity.