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1187941-65-6

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1187941-65-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1187941-65-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,7,9,4 and 1 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1187941-65:
(9*1)+(8*1)+(7*8)+(6*7)+(5*9)+(4*4)+(3*1)+(2*6)+(1*5)=196
196 % 10 = 6
So 1187941-65-6 is a valid CAS Registry Number.

1187941-65-6Downstream Products

1187941-65-6Relevant articles and documents

The P1 N-isopropyl motif bearing hydroxyethylene dipeptide isostere analogues of aliskiren are in vitro potent inhibitors of the human aspartyl protease renin

Yamaguchi, Yasuchika,Menear, Keith,Cohen, Nissim-Claude,Mah, Robert,Cumin, Frédéric,Schnell, Christian,Wood, Jeanette M.,Maibaum, Jürgen

scheme or table, p. 4863 - 4867 (2010/05/18)

Novel nonpeptide small molecule renin inhibitors bearing an N-isopropyl P1 motif were designed based on initial lead structures 1 and aliskiren (2). (P3-P1)-Benzamide derivatives such as 9a and 34, as well as the corresponding P1 basic tertiary amine derivatives 10 and 35 were found to display low nanomolar inhibition against human renin in vitro.

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