118812-48-9

Basic information

• Product Name: [(R)-2-Methyl-1-(4-methyl-3,5-dioxo-[1,2,4]oxadiazolidine-2-carbonyl)-butyl]-carbamic acid benzyl ester
• CAS NO: 118812-48-9
• Molecular Weight: 363.37
• Mol File: 118812-48-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [(R)-2-Methyl-1-(4-methyl-3,5-dioxo-[1,2,4]oxadiazolidine-2-carbonyl)-butyl]-carbamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(R)-2-Methyl-1-(4-methyl-3,5-dioxo-[1,2,4]oxadiazolidine-2-carbonyl)-butyl]-carbamic acid benzyl ester(118812-48-9)
• EPA Substance Registry System: [(R)-2-Methyl-1-(4-methyl-3,5-dioxo-[1,2,4]oxadiazolidine-2-carbonyl)-butyl]-carbamic acid benzyl ester(118812-48-9)

Safety Data

• Hazardous Substances Data: 118812-48-9(Hazardous Substances Data)

Upstream product

• 3160-59-6 N-benzyloxycarbonyl-D-isoleucine 
• 115491-90-2 2,2'-carbonyl bis-(3,5-dioxo-4-methyl-1,2,4-oxadiazolidine) 

Downstream Products

• 118812-53-6 (R)-4-Benzyloxycarbonylamino-5-methyl-3-oxo-heptanoic acid ethyl ester 
• 118812-59-2 (3S,4R,5S)-anti-isostatine 

Relevant articles and documents

AN IMPROVED SYNTHESIS OF β-KETO ESTER UNITS IN DIDEMNINS, USING 2,2'-CARBONYL-BIS(3,5-DIOXO-4-METHYL-1,2,4-OXADIAZOLIDINE).

Activation of N-protected α-amino acids and O-protected α-hydroxy acids with 2,2'-carbonyl-bis(3,5-dioxo-4-methyl-1,2,4-oxadiazolidine) 6 provide a stable activated intermediate 7 suitable for the synthesis of β-keto ester 8.This activation was used in th