1190310-15-6 Usage
General Description
5-Fluoro-1H-pyrrolo[2,3-b]pyridine-4-carbaldehyde is a chemical compound with the molecular formula C8H5FN2O. It is a pyrrolopyridine derivative that contains a fluorine atom and an aldehyde functional group. 5-Fluoro-1H-pyrrolo[2,3-b]pyridine-4-carbaldehyde is used in organic synthesis and chemical research as a building block for the preparation of various pharmaceuticals and agrochemicals. It has potential applications in the development of new drugs and crop protection agents due to its unique structural properties and biological activities. Additionally, its fluorinated structure may provide enhanced stability and bioavailability in drug formulations. As a result, 5-Fluoro-1H-pyrrolo[2,3-b]pyridine-4-carbaldehyde is of interest to researchers and industry professionals in the fields of medicinal chemistry, pharmaceuticals, and agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 1190310-15-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,0,3,1 and 0 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1190310-15:
(9*1)+(8*1)+(7*9)+(6*0)+(5*3)+(4*1)+(3*0)+(2*1)+(1*5)=106
106 % 10 = 6
So 1190310-15-6 is a valid CAS Registry Number.
1190310-15-6Relevant articles and documents
Preparation method of 5-fluoro-1H-pyrrolo[2,3-b]pyridine-4-carbaldehyde
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Paragraph 0028; 0030-0033; 0036-0039, (2019/08/20)
The invention discloses a preparation method of 5-fluoro-1H-pyrrolo[2,3-b]pyridine-4-carbaldehyde, comprising the following steps: dissolving 5-fluoro-1H-pyrrolo[2,3-b]pyridine in a solvent, and adding triisopropylchlorosilane under alkaline conditions for reaction to obtain 5-fluoro-1-triisopropylsilylpyrrolo[2,3-b]pyridine; dissolving 5-fluoro-1-isopropylsilylpyrrolo[2,3-b]pyridine in a solvent,adding a formylating reagent under alkaline conditions for reaction, and after the reaction, adding a desiliconization reagent for in situ deprotection to obtain 5-fluoro-1H-pyrrolo[2,3-b]pyridine-4-carbaldehyde. The preparation method for the 5-fluoro-1H-pyrrolo[2,3-b]pyridine-4-carbaldehyde of the invention is a two-step method with advantages of short preparation route, easy-to-obtain raw materials, simple operation, remarkably reduced production cost and no generated heavy metal solid waste. The method is suitable for large-scale production of 5-fluoro-1H-pyrrolo[2,3-b]pyridine-4-carbaldehyde.
