119103-15-0

Basic information

• Product Name: 1-AZABICYCLO[2.2.1]HEPTANE-4-CARBOXYLIC ACID
• Synonyms: 1-AZABICYCLO[2.2.1]HEPTANE-4-CARBOXYLIC ACID;1-Azabicyclo[2.2.1]heptane-4-carboxylic acid hydrobromide
• CAS NO: 119103-15-0
• Molecular Formula: C7H11NO2
• Molecular Weight: 141.17
• Mol File: 119103-15-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 257.7±23.0 °C(Predicted)
• Appearance: /
• Density: 1.29±0.1 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.77±0.20(Predicted)
• CAS DataBase Reference: 1-AZABICYCLO[2.2.1]HEPTANE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 1-AZABICYCLO[2.2.1]HEPTANE-4-CARBOXYLIC ACID(119103-15-0)
• EPA Substance Registry System: 1-AZABICYCLO[2.2.1]HEPTANE-4-CARBOXYLIC ACID(119103-15-0)

Safety Data

• Hazardous Substances Data: 119103-15-0(Hazardous Substances Data)

Usage

General Description

1-AZABICYCLO[2.2.1]HEPTANE-4-CARBOXYLIC ACID is a chemical compound with a complex molecular structure. It is a bicyclic compound containing a seven-membered ring with a nitrogen atom. The carboxylic acid functional group in the molecule makes it acidic in nature. This chemical may have various applications in the pharmaceutical industry, such as in the development of drugs and medications. Its unique structure and properties make it an interesting compound for further research and potential uses in different fields.

Upstream product

• 119102-24-8 ethyl 1-azabicyclo<2.2.1>hept-4-yl carboxylate 
• 129656-27-5 ethyl 1-azabicyclo[2.2.1]heptane-4-carboxylate hydrobromide 
• 119102-90-8 7-benzyl-7-aza-2-oxaspiro<4.4>nonan-1-one 
• 17012-21-4 1-benzylpyrrolidine-3-carboxylic acid methyl ester 
• 119102-91-9 1-Benzyl-4-ethoxycarbonyl-1-azonia-bicyclo[2.2.1]heptane; bromide 

Downstream Products

• 119102-22-6 methyl 1-azabicyclo<2.2.1>heptane-4-carboxylate 
• 119103-16-1 1-Aza-bicyclo[2.2.1]heptane-4-carbonyl chloride 
• 126344-06-7 4-acetyl-1-azabicyclo[2.2.1]heptane 
• 1338705-70-6 C₂₉H₃₁ClN₂O₅ 

Relevant articles and documents

CEPHEM COMPOUND HAVING CATECHOL GROUP

A compound of the formula: wherein X is -N=, -CH=, or the like; W is -CH2- or the like; U is -S- or the like; R1 and R2 are each independently hydrogen, halogen, optionally substituted lower alkyl, or the like; R3/su

Substituent variation in azabicyclic triazole- and tetrazole-based muscarinic receptor ligands

The effect of variation of the 1-azabicyclic substituent on the novel 1,2,3-triazol-4-yl-, 1,2,4-triazol-1-yl-, tetrazol-5-yl-, and tetrazol-2-yl- based muscarinic receptor ligands has been studied, and the exo- azabicyclic[2.2.1]hept-3-yl substituent was found to give the most potent and efficacious compounds. In addition, variation of the second substituent on 1,2,4-triazol-1-yl- and tetrazol-2-yl-based muscarinic receptor ligands has yielded a series of novel compounds with high potencies and efficacies, ranging from full agonists to antagonists. Small lipophilic electron withdrawing substituents give potent but low efficacy compounds, while small polar electron donating substituents give potent and efficacious compounds. The activity of these compounds is described in terms of a model of the receptor involving lipophilic and hydrogen bonding interactions. These compounds provide muscarinic ligands with high potency and a range of efficacies suitable for testing as candidate drugs in the treatment of Alzheimer's disease.