119106-85-3

Basic information

• Product Name: ala-lys-pro-ser-tyr-hyp-hyp-thr-tyr-lys
• CAS NO: 119106-85-3
• Molecular Formula: C₅₅H₈₂N₁₂O₁₇
• Molecular Weight: 1183.32
• Mol File: 119106-85-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ala-lys-pro-ser-tyr-hyp-hyp-thr-tyr-lys(CAS DataBase Reference)
• NIST Chemistry Reference: ala-lys-pro-ser-tyr-hyp-hyp-thr-tyr-lys(119106-85-3)
• EPA Substance Registry System: ala-lys-pro-ser-tyr-hyp-hyp-thr-tyr-lys(119106-85-3)

Safety Data

• Hazardous Substances Data: 119106-85-3(Hazardous Substances Data)

Upstream product

• 35661-39-3 N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine 
• 71989-31-6 Fmoc-Pro-OH 
• 71989-33-8 Fmoc-Ser(tBu)-OH 
• 71989-38-3 Fmoc-Tyr(tBu)-OH 
• 71989-26-9 Fmoc-Lys(tert-butoxycarbonyl) 
• 71989-35-0 Fmoc-Thr(tBu)-OH 
• 268729-12-0 (2S,4R)-4-tert-butoxy-1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidine-2-carboxylic acid 

Relevant articles and documents

NEW CONJUGATES OF MONTELUKAST AND PEPTIDES

There is provided a peptide-containing compound that comprises a peptide component which is an amino acid sequence of from 2 to 45 amino acids, which peptide component is covalently bonded to one or more compounds of the formula (I), wherein: R1 is selected from the group consisting of -C(CH3)2OH, -COCH3, -C(CH3)=CH2 and -C(CH3)2H; and n is 0, 1 or 2, as well as regioisomers, stereoisomers, and pharmaceutically-or cosmetically-acceptable salts of said peptide-containing compound. The compound of formula I is preferably montelukast, montelukast styrene or hydrogenated montelukast styrene. The peptide-containing compound is particularly useful in the treatment of inflammation, including wounds, hemorrhoids, burns, psoriasis, acne, atopic dermatitis, allergic rhinitis, allergic conjunctivitis, chronic obstructive pulmonary disease, inflammatory bowel disease (such as. ulcerative colitis). The peptide-containing compound is also useful in the treatment of idiopathic pulmonary fibrosis.