1193-66-4Relevant articles and documents
PRODUCTION METHOD FOR BICYCLIC AMINE COMPOUND
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Paragraph 0050; 0051; 0056, (2019/01/06)
PROBLEM TO BE SOLVED: To provide a production method for obtaining bicyclic amine compounds with high reaction yield. SOLUTION: The method includes subjecting a hydroxyl group-containing cyclic amine compound of a formula (1) to intramolecular dehydration in a gas phase in the presence of a solid catalyst containing alkaline earth metal phosphate and alkali metal salt [in the formula (1), R1 to R8 each independently represent a hydrogen atom, a C1 to 4 alkyl group, a hydroxy group, a hydroxymethyl group, or a C1 to 4 alkoxy group; X represents a carbon atom or a nitrogen atom; Y represents an alkyl group, a hydroxy group, a C1 to 4 hydroxyalkyl group, or a C1 to 4 aminoalkyl group]. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT
METHOD FOR PRODUCING BICYCLIC AMINE COMPOUND
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Paragraph 0047; 0054, (2017/11/15)
PROBLEM TO BE SOLVED: To provide a stable production method for a bicyclic amine compound that inhibits the generation of by-products in the production of a bicyclic amine. SOLUTION: The present invention provides a method for producing a bicyclic amine compound which employs a catalyst comprising an inorganic support and an alkali metal phosphate, and further comprising alkaline earth metal hydroxide and/or hydroxyapatite in an amount of 1.5 wt.% or more and less than 15 wt.% relative to the inorganic support. SELECTED DRAWING: None COPYRIGHT: (C)2017,JPO&INPIT