1196-70-9 Usage
Description
Indole-6-carboxaldehyde is an organic compound with the chemical formula C9H7NO and a molecular weight of 145.16 g/mol. It is a crystalline solid that serves as a versatile reactant in various organic synthesis processes.
Uses
Used in Pharmaceutical Industry:
Indole-6-carboxaldehyde is used as a reactant in the preparation of analogs of botulinum neurotoxin serotype A protease inhibitors. This application is crucial for developing potential therapeutic agents against botulinum neurotoxin, which is responsible for causing botulism, a severe and sometimes fatal illness.
Used in Organic Synthesis:
Indole-6-carboxaldehyde is used as a reactant in the synthesis of stilbene-based antitumor agents. Stilbenes are a class of organic compounds known for their potential anti-cancer properties, and Indole-6-carboxaldehyde plays a significant role in their synthesis, contributing to the development of new cancer treatments.
Used in Chemical Research:
Indole-6-carboxaldehyde is used as a reactant in the acid-catalyzed preparation of aromatic gem-dihalides from aldehydes and acid halides. This process is essential for the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals, showcasing the compound's utility in chemical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 1196-70-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,9 and 6 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1196-70:
(6*1)+(5*1)+(4*9)+(3*6)+(2*7)+(1*0)=79
79 % 10 = 9
So 1196-70-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H7NO/c11-6-7-1-2-8-3-4-10-9(8)5-7/h1-6,10H
1196-70-9Relevant articles and documents
SYNTHESIS AND REACTIVITY OF 6-(FLUOROMETHYL)INDOLE AND 6-(DIFLUOROMETHYL)INDOLE
Woolridge, Elisa M.,Rokita, Steven E.
, p. 6117 - 6120 (1989)
The N-1 BOC protected precursors of 6-(fluoromethyl)indole and 6-(difluoromethyl)indole were prepared and deprotected via flash vacuum thermolysis.The stability of these newly prepared, unprotected indole derivatives has been characterized and compared to that of a previously known compound, 6(trifluoromethyl)indole.
N-(2-ARYLETHYL) BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR
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, (2016/01/25)
The present invention relates to the use compounds of formula I which are antagonists of the 5-HT 6 receptor, for treating a cognitive disorder selected from the group consisting of age-related cognitive decline, mild cognitive impairment and dementia
HETEROCYCLIC COMPOUNDS, METHODS OF MAKING THEM AND THEIR USE IN THERAPY
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Page 46-47; 93-94, (2010/02/07)
In part, the present invention is directed to antibacterial compounds of formula (I) wherein A is a bicyclic heteroaryl ring or a tricyclic ring and R2 is an heterocyclic residue; L is a bond, or L is alkyl, alkenyl or cycloalkyl.