1198409-01-6

Basic information

• Product Name: (1S)-1-methyl-2-oxo-2-tetrahydro-1H-pyrrolylethyl N-(p-methoxyphenyl)-2-amino-3-cyclopropylpropanoate
• Synonyms: (1S)-1-methyl-2-oxo-2-tetrahydro-1H-pyrrolylethyl N-(p-methoxyphenyl)-2-amino-3-cyclopropylpropanoate
• CAS NO: 1198409-01-6
• Molecular Weight: 360.453
• Mol File: 1198409-01-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S)-1-methyl-2-oxo-2-tetrahydro-1H-pyrrolylethyl N-(p-methoxyphenyl)-2-amino-3-cyclopropylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (1S)-1-methyl-2-oxo-2-tetrahydro-1H-pyrrolylethyl N-(p-methoxyphenyl)-2-amino-3-cyclopropylpropanoate(1198409-01-6)
• EPA Substance Registry System: (1S)-1-methyl-2-oxo-2-tetrahydro-1H-pyrrolylethyl N-(p-methoxyphenyl)-2-amino-3-cyclopropylpropanoate(1198409-01-6)

Safety Data

• Hazardous Substances Data: 1198409-01-6(Hazardous Substances Data)

Upstream product

• 1198408-99-9 (1S)-1-methyl-2-oxo-2-tetrahydro-1H-pyrrolylethyl 2-bromo-3-cyclopropylpropanoate 
• 104-94-9 4-methoxy-aniline 

Downstream Products

• 121786-39-8 (R)-2-amino-3-cyclopropylpropanoic acid 
• 102735-53-5 (2S)-2-amino-3-cyclopropylpropanoic acid 
• 1198409-03-8 N-(p-methoxyphenyl)-2-amino-3-cyclopropylbutanoic acid 

Relevant articles and documents

METHOD OF PRODUCING OPTICALLY ACTIVE AMINO ACID DERIVATIVE

The present application relates to a method for producing an optically active α-amino acid derivative, comprising steps of reacting an α-haloester derivative represented by the general formula (1): of which alcohol part of the ester group is an optically active alcohol derivative, with an amine compound; then deprotecting the obtained compound; further carrying out an ester exchange reaction. According to the present invention method, it is possible to easily produce an optically active α-amino acid ester derivative which is useful as an intermediate for drugs with high selectivity.