120205-98-3

Basic information

• Product Name: tert-butyl (N)-benzyl(1-oxopropan-2-yl)carbamate
• Synonyms: tert-butyl (N)-benzyl(1-oxopropan-2-yl)carbamate
• CAS NO: 120205-98-3
• Molecular Weight: 263.337
• Mol File: 120205-98-3.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: tert-butyl (N)-benzyl(1-oxopropan-2-yl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (N)-benzyl(1-oxopropan-2-yl)carbamate(120205-98-3)
• EPA Substance Registry System: tert-butyl (N)-benzyl(1-oxopropan-2-yl)carbamate(120205-98-3)

Safety Data

• Hazardous Substances Data: 120205-98-3(Hazardous Substances Data)

Upstream product

• 54159-18-1 ethyl 2-(benzylamino)propanoate 
• 100-52-7 benzaldehyde 
• 6940-80-3 (S)-N-benzylalaninol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 209266-07-9 methyl (S)-2-[(N-benzyl)-(N-t-butoxycarbonyl)amino]propanoate 
• 158380-71-3 tert-butyl (S)-benzyl(2-hydroxy-1-methylethyl)carbamate 
• 139190-69-5 N-Benzyl-N-tert-butoxycarbonyl-L-alanine ethyl ester 
• 120571-59-7 N-benzyl-N-(tert-butoxycarbonyl)-D-alanine methyl ester 
• 100-39-0 benzyl bromide 
• 31022-10-3 N-benzyl-L-alanine methyl ester 
• 120571-58-6 N-benzyl D-alanine methyl ester 

Downstream Products

• 120206-03-3 (2RS,1'R)-2-<(1'-N-benzyl-N-tert-butoxycarbonylamino)ethyl>-2,3-dihydropyran-4-one 
• 139190-67-3 (3R,4R,5S)-1-Benzyl-3-methoxycarbonyl-4,5-dimethyl-2-pyrrolidinone 
• 123807-64-7 (4R,5S)-1-Benzyl-4,5-dimethyl-2-pyrrolidinone 
• 214632-86-7 (Z)-(4S,8S)-8-Benzylamino-non-6-en-4-ol 
• 445432-15-5 benzyl-(1-methyl-4-oxo-pentyl)-carbamic acid tert-butyl ester 
• 361341-91-5 tert-butyl N-benzyl-N-[(1S,2E)-4-hydroxy-1-methyl-2-butenyl]carbamate 
• 214632-83-4 3-benzyl-4-methyl-5-vinyloxazolidin-2-one 
• 151929-50-9 ethyl (2E,4S)-4-[benzyl(tert-butoxycarbonyl)amino]pent-2-enoate 
• 497968-33-9 (1S,2S)-N-benzyl-N-[2-(5-methylfuran-2-yl)-2-hydroxy-1-methylethyl]carbamic acid tert-butyl ester 
• 399559-53-6 Benzyl-[(1S,2R)-2-hydroxy-1-methyl-4-((R)-toluene-4-sulfinyl)-pent-4-enyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

Oxazolidinones and 2,5-Dihydrofurans via Zinc-Catalyzed Regioselective Allenylation Reactions of l -α-Amino Aldehydes

The simultaneous control of diastereoselectivity and regioselectivity in Zn-catalyzed allenylation reactions of N-protected l-α-amino aldehydes is reported. A reversal in diastereoselectivity could be realized by variation of the α-amino aldehyde protecti

Metal-free, mild, nonepimerizing, chemo- and enantio- or diastereoselective N-alkylation of amines by alcohols via oxidation/imine-iminium formation/reductive amination: A pragmatic synthesis of octahydropyrazinopyridoindoles and higher ring analogues

A mild step and atom-economical nonepimerizing chemo- and enantioselective N-alkylating procedure has been developed via oxidation/imine-iminium formation/reduction cascade using TEMPO-BAIB-HEH-Bronsted acid catalysis in DMPU as solvent and a stoichiometric amount of amine. The optimized conditions were further extended for the nonenzymatic kinetic resolution of the chiral amine thus formed under nonenzymatic in situ hydrogen-transfer conditions using VAPOL-derived phosphoric acid (VAPOL-PA) as the Bronsted acid catalyst. The enantioselective cascade of the presented reaction was successfully utilized in the synthesis of octahydropyrazinopyridoindole and its higher ring analogues.

Scope and limitations of the alkylidene carbene 1,5-CH insertion reactions of α-amino acid-derived substrates

A range of α-amino acid-derived cyclisation precursors were synthesised from suitably protected α-amino esters, via a Dibal-H/Wittig/catalytic hydrogenation strategy and each of these was subjected to alkylidene carbene-forming conditions (lithio(trimethy