1202177-91-0

Basic information

• Product Name: (E)-(3,4-difluorophenyl){5-[(7-pyrazolo[1,5-b]pyridazin-3-yl-2,7-diazaspiro[4.4]non-2-yl)methyl]-2-pyridinyl}methanone O-ethyloxime
• Synonyms: (E)-(3,4-difluorophenyl){5-[(7-pyrazolo[1,5-b]pyridazin-3-yl-2,7-diazaspiro[4.4]non-2-yl)methyl]-2-pyridinyl}methanone O-ethyloxime
• CAS NO: 1202177-91-0
• Molecular Weight: 517.581
• Mol File: 1202177-91-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-(3,4-difluorophenyl){5-[(7-pyrazolo[1,5-b]pyridazin-3-yl-2,7-diazaspiro[4.4]non-2-yl)methyl]-2-pyridinyl}methanone O-ethyloxime(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-(3,4-difluorophenyl){5-[(7-pyrazolo[1,5-b]pyridazin-3-yl-2,7-diazaspiro[4.4]non-2-yl)methyl]-2-pyridinyl}methanone O-ethyloxime(1202177-91-0)
• EPA Substance Registry System: (E)-(3,4-difluorophenyl){5-[(7-pyrazolo[1,5-b]pyridazin-3-yl-2,7-diazaspiro[4.4]non-2-yl)methyl]-2-pyridinyl}methanone O-ethyloxime(1202177-91-0)

Safety Data

• Hazardous Substances Data: 1202177-91-0(Hazardous Substances Data)

Upstream product

• 1137951-00-8 (6-{(E)-(3,4-Difluorophenyl)[(ethyloxy)imino]methyl}-3-pyridinyl)methyl methanesulfonate 
• 1177266-41-9 tert-butyl 7-benzyl-2,7-diazaspiro[4.4]nonane-2-carboxylate 
• 1017599-32-4 (E)-(3,4-difluorophenyl)[5-(hydroxymethyl)pyridine-2-yl]methanone O-ethyloxime 
• 1137949-68-8 3-bromopyrazolo[1,5-b]pyridazine 
• 1202179-20-1 (E)-[5-(2,7-diazaspiro[4.4]non-2-ylmethyl)-2-pyridinyl](3,4-difluorophenyl)methanone O-ethyloxime 
• 885275-27-4 2-benzyl 2,7-diaza-spiro-[4.4]nonane 
• 2306252-57-1 2,7-diazaspiro[4.4]-nonane-2-carboxylic acid tert-butyl ester 

Relevant articles and documents

SPIRODIAMINE-DIARYL KETOXIME DERIVATIVE

[Problem] To provide a melanin concentrating hormone receptor antagonist useful as medicines for central system disorders, cardiovascular disorders, metabolic disorders. [Means for Resolution] Provided are compound of a formula (I): [wherein R1 a and R1 b each are a hydrogen atom, etc.; R2 is a hydrogen atom, a C1-6 alkyl, etc.; Ar1 is a 6-membered aromatic carbocyclic group or a 6-membered aromatic nitrogen-containing heterocyclic group; Ar2 is a group to be formed by removing two hydrogen atoms from a 6-membered aromatic carbon ring, a 6-membered aromatic nitrogen-containing hetero ring, etc.; Ar3 is a mono- or bi-cyclic aromatic carbon ring or aromatic hetero ring; m1, m2, m3 and m4 each are independently 0, 1, 2, 3 or 4, provided that the total of m1 and m2 is from 2 to 6, the total of m3 and m4 is from 2 to 6]. The compounds are useful as medicines for central system disorders, cardiovascular disorders, metabolic disorders.