1203494-36-3

Basic information

• Product Name: 4-(2,6-difluorophenylsulfonyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-ylsulfonyl)piperazin-2-one
• Synonyms: 4-(2,6-difluorophenylsulfonyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-ylsulfonyl)piperazin-2-one
• CAS NO: 1203494-36-3
• Molecular Weight: 474.463
• Mol File: 1203494-36-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(2,6-difluorophenylsulfonyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-ylsulfonyl)piperazin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2,6-difluorophenylsulfonyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-ylsulfonyl)piperazin-2-one(1203494-36-3)
• EPA Substance Registry System: 4-(2,6-difluorophenylsulfonyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-ylsulfonyl)piperazin-2-one(1203494-36-3)

Safety Data

• Hazardous Substances Data: 1203494-36-3(Hazardous Substances Data)

Upstream product

• 63758-12-3 6-chlorosulfonyl-1,4-benzodioxane 
• 1095875-42-5 4-(2,6-difluorophenylsulfonyl)piperazin-2-one 

Relevant articles and documents

ACTIVATORS OF HUMAN PYRUVATE KINASE

Disclosed are pyruvate kinase M2 activators, which are, bis sulfonamide piperazinyl compounds of Formula (I) and 2,4-disubstituted 4H-thieno[3,2-b]pyrrole-2-(substituted benzyl)pyridazin-3(2H)ones of Formula (II), wherein L and R1 to R16 are as defined herein, that are useful in treating a number of diseases that are treatable by the activation of PKM2, for example, cancer and anemia, Formulas (I); (II).