1203555-46-7

Basic information

• Product Name: 5,6-dihydro-6-(naphthalen-1-yl)-2-(phenylamino)pyrido[2,3-d]pyrimidin-7(8H)-one
• Synonyms: 5,6-dihydro-6-(naphthalen-1-yl)-2-(phenylamino)pyrido[2,3-d]pyrimidin-7(8H)-one
• CAS NO: 1203555-46-7
• Molecular Weight: 366.422
• Mol File: 1203555-46-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5,6-dihydro-6-(naphthalen-1-yl)-2-(phenylamino)pyrido[2,3-d]pyrimidin-7(8H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-dihydro-6-(naphthalen-1-yl)-2-(phenylamino)pyrido[2,3-d]pyrimidin-7(8H)-one(1203555-46-7)
• EPA Substance Registry System: 5,6-dihydro-6-(naphthalen-1-yl)-2-(phenylamino)pyrido[2,3-d]pyrimidin-7(8H)-one(1203555-46-7)

Safety Data

• Hazardous Substances Data: 1203555-46-7(Hazardous Substances Data)

Upstream product

• 57597-62-3 3,3-dimethoxypropionitrile 
• 6685-76-3 phenylguanidinium hydrogencarbonate 
• 335208-46-3 2-naphthalen-1-yl-acrylic acid methyl ester 

Relevant articles and documents

An unusual Michael addition of 3,3-dimethoxypropanenitrile to 2-aryl acrylates: A convenient route to 4-unsubstituted 5,6-dihydropyrido[2,3-d] pyrimidines

(Chemical Equation Presented) An unusual Michael addition between 2-aryl-substituted acrylates and 3,3-dimethoxypropanenitrile which leads, depending on the reaction temperature (60 or -78 °C, respectively), to a 4-methoxymethylene-substituted 4-cyanobutyric ester or to a 4-dimethoxymethyl 4-cyanobutyric ester is described. These compounds can be subsequently converted to 4-unsubstituted pyrido[2,3-d]-pyrimidines upon treatment with a guanidine system under microwave irradiation.