120407-73-0

Basic information

• Product Name: 4-Butoxy-1,1,1-trofluoro-3-buten-2-one
• Synonyms: 4-Butoxy-1,1,1-trofluoro-3-buten-2-one;4-Butoxy-1,1,1-trifluorobut-3-en-2-one;3-Buten-2-one, 4-butoxy-1,1,1-trifluoro-
• CAS NO: 120407-73-0
• Molecular Formula: C₈H₁₁F₃O₂
• Molecular Weight: 196.1669496
• Mol File: 120407-73-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 155℃
• Flash Point: 47℃
• Appearance: /
• Density: 1.126
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-Butoxy-1,1,1-trofluoro-3-buten-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Butoxy-1,1,1-trofluoro-3-buten-2-one(120407-73-0)
• EPA Substance Registry System: 4-Butoxy-1,1,1-trofluoro-3-buten-2-one(120407-73-0)

Safety Data

• Hazardous Substances Data: 120407-73-0(Hazardous Substances Data)

Usage

General Description

4-Butoxy-1,1,1-trifluoro-3-buten-2-one is a chemical compound with the molecular formula C7H9F3O2. It is a colorless, liquid with a slightly sweet odor and is used as a synthetic intermediate in the production of other compounds. It is also used as a solvent in various industrial processes. The compound is highly reactive and can undergo various chemical reactions to form new compounds. It is important to handle this chemical with care as it can be hazardous if not used properly.

Upstream product

• 111-34-2 -butyl vinyl ether 
• 407-25-0 trifluoroacetic anhydride 
• 109-92-2 ethyl vinyl ether 
• 1522-22-1 1,1,1,5,5,5-hexafluoroacetylacetone 

Downstream Products

• 21045-62-5 4-(diethylamino)-1,1,1-trifluorobut-3-en-2-one 
• 116548-03-9 2-hydroxy-6-trifluoromethylpyridine-3-carboxamide 
• 144740-55-6 1,2-dihydro-2-oxo-6-(trifluoromethyl)pyridine-3-carboxylic acid methyl ester 
• 116548-04-0 2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile 
• 3108-32-5 1,1,1-trifluoro-4-phenylbut-3-en-2-one 
• 116548-03-9 2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide 

Relevant articles and documents

GHRELIN O-ACYLTRANSFERASE INHIBITORS

This invention relates to novel compounds according to Formula (I) which are inhibitors of ghrelin O-acyltransferase (GOAT), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment

Synthesis of novel pyrido[3′,2′:4,5]furo[3,2-d]pyrimidine derivatives and their cytotoxic activity

The 3-amino-6-(trifluoromethyl)furo[2,3-b]pyridine-2-carbohydrazide (5) was prepared from 3-cyano-6-trifluoromethyl-2(1H)pyridone (2) in series of steps via selective O-alkylation, Thorpe-Ziegler cyclization followed by reaction with hydrazine hydrate. The 2-carbohydrazide (5) was further reacted with aliphatic acids under different reaction temperatures to form a series of novel N-acylfuro[2,3-b]pyridine-2-carbohydrazide (6) and pyrido[3′,2′:4,5]furo[3,2-d]pyrimidine derivatives (7). All the compounds 6 and 7 were screened for cytotoxic activity against breast carcinoma MD Anderson-Metastatic Breast (MDA-MB) 231 (aggressive) cell lines at 10 μM concentration. Compounds 6a, 6b, and 6c showed promising activity.

PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARTION AND THEIR USE

Compounds of the formula (I), or salts thereof, in which R1 to R4 are as defined in formula (I) of claim 1 are suitable as useful-plant-protecting agents for reducing or preventing harmful effects of agrochemicals on the useful plants and their method of preparation are described.