1204573-53-4Relevant articles and documents
Positive allosteric modulators of 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid receptors belonging to 4-cyclopropyl-3,4-dihydro-2 H -1,2,4-pyridothiadiazine dioxides and diversely chloro-substituted 4-cyclopropyl-3,4-dihydro-2 H -1,2,4-benzot
Francotte, Pierre,N?rholm, Ann-Beth,Deva, Taru,Olsen, Lars,Frydenvang, Karla,Goffin, Eric,Fraikin, Pierre,De Tullio, Pascal,Challal, Sylvie,Thomas, Jean-Yves,Iop, Fabrice,Louis, Caroline,Botez-Pop, Iuliana,Lestage, Pierre,Danober, Laurence,Kastrup, Jette S.,Pirotte, Bernard
, p. 9539 - 9553 (2015/01/09)
Two 4-ethyl-substituted pyridothiadiazine dioxides belonging to α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor positive allosteric modulators were cocrystallized with the GluA2 ligand binding domain in order to decipher the impact of
