1204589-64-9Relevant articles and documents
Highly enantio- and diastereoselective synthesis of α- trifluoromethyldihydropyrans using a novel bifunctional piperazine-thiourea catalyst
Li, Peng,Chai, Zhuo,Zhao, Sheng-Li,Yang, Ying-Quan,Wang, Hai-Feng,Zheng, Chang-Wu,Cai, Yue-Peng,Zhao, Gang,Zhu, Shi-Zheng
supporting information; experimental part, p. 7369 - 7371 (2010/06/14)
The first enantioselective Michael addition of α-cyanoketones to α,β-unsaturated trifluoromethyl ketones using a novel piperazine-thiourea catalyst was described. The resulting α- trifluoromethyldihydropyrans were obtained in high yields and with up to 95