1204603-59-7

Basic information

• Product Name: 6-chloromethyl-2-(3,4-dimethoxyphenyl)-1-benzopyran-4-one
• CAS NO: 1204603-59-7
• Molecular Weight: 330.768
• Mol File: 1204603-59-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-chloromethyl-2-(3,4-dimethoxyphenyl)-1-benzopyran-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloromethyl-2-(3,4-dimethoxyphenyl)-1-benzopyran-4-one(1204603-59-7)
• EPA Substance Registry System: 6-chloromethyl-2-(3,4-dimethoxyphenyl)-1-benzopyran-4-one(1204603-59-7)

Safety Data

• Hazardous Substances Data: 1204603-59-7(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 4143-62-8 3',4'-dimethoxyflavone 

Downstream Products

• 1204603-68-8 2-(3,4-dimethoxyphenyl)-6-morpholinomethyl-1-benzopyran-4-one 
• 1204603-70-2 2-(3,4-dimethoxyphenyl)-6-(4-piperazinomethyl)-1-benzopyran-4-one 
• 1204603-69-9 2-(3,4-dimethoxyphenyl)-6-(4-toluidinomethyl)-1-benzopyran-4-one 
• 1204603-71-3 4-{4-oxo-2-(3,4-dimethoxyphenyl)-6-benzopyranylmethylamino}-1-benzene-sulfonamide 

Relevant articles and documents

Synthesis of 6-aminomethyl derivatives of benzopyran-4-one with dual biological properties: Anti-inflammatory-analgesic and antimicrobial

A series of 6-aminomethyl-2-aryl-1-benzopyran-4-one derivatives (10-24) were synthesized. The compounds were tested for anti-inflammatory, analgesic, ulcerogenic and lipid peroxidation actions. Among the tested compounds, six compounds 11, 13, 16, 18, 21 and 23 showed higher degree of anti-inflammatory activity (>75% activity of standard drug ibuprofen). In addition to remarkable anti-inflammatory activity, analgesic activity was found to be comparable with that of the standard drug ibuprofen. Compounds 16 and 21 showed a significant GI protection (with respect to ulcerogenesis) and a marked decrease in lipid peroxidation values whereas compounds 11 and 16 were found to possess antimicrobial activity against Staphylococcus aureus, Escherichiacoli, Rhizopus oryza and Penicillum citrum with an MIC of 10 μg/mL.