120952-09-2Relevant articles and documents
KINETICS OF THE REACTIONS OF A 2-BROMO-N-ETHYLPYRIDINIUM SALT WITH PRIMARY AROMATIC AMINES IN ACETONITRILE
Litvinenko, L. M.,Titskii, G. D.,Mitchenko, E. S.
, p. 1553 - 1556 (2007/10/02)
The kinetics of the reactions of 2-bromo-N-ethylpyridinium bromide with ringsubstituted aromatic amines in acetonitrile at 25 deg C were investigated.The effect of the substituents in the benzene ring of the aromatic amines on the kinetics of nucleophilic substitution with the halogenopyridinium salt is described by a correlation equation with the ?0 constants.The reactivity of aliphatic and aromatic amines in reactions with 2-bromo-N-ethylpyridinium bromide in acetonitrile is described by a single correlation equation, which defines the joint contribution from electronic and steric factors of the substituets in the nucleophilic reagent.