121238-80-0Relevant articles and documents
THE CHEMISTRY OF N-SUBSTITUTED BENZOTRIAZOLES. PART 18. A STUDY OF THE INFLUENCE OF STRUCTURE ON THE 1- TO 2-(N,N-DIALKYLAMINOALKYL)BENZOTRIAZOLE EQUILIBRIUM
Katritzky, Alan R.,Yannakopoulou, Konstantina
, p. 1121 - 1134 (2007/10/02)
The equilibrium constants, the associated free energies for the equilibria, and the free energies of activation for the isomerization process of a series of 1- and 2-(N,N-dialkylaminoalkyl)benzotriazoles of types (8)-(11) were calculated from the variable temperature 1H-nmr spectra.Trends in the magnitudes of these energies and equilibrium constants are correlated with the molecular structure.
A New General Method for the Synthesis of Tertiary Propargylamines (N,N-Dialkyl-2-alkynamines)
Katritzky, Alan R.,Gallos, John K.,Yannakopoulou, Konstantina
, p. 31 - 33 (2007/10/02)
A new method has been developed for the preparation of propargylamines, compounds of pharmaceutical interest.The method employs mild conditions, affords good overall yields, and is succesfully applied even in cases where other methods fail.
