12125-01-8 Usage
Description
Ammonium fluoride is a white crystalline solid that is soluble in water and noncombustible. It is corrosive to aluminum and is used in various applications such as chemical analysis, brewing, and as a preservative for wood. It is also a toxic substance.
Uses
Used in Chemical Analysis:
Ammonium fluoride is used as a reagent for chemical analysis, providing safe deprotection strategy for the tert-butyldimethylsilyl (TBS) group during RNA synthesis.
Used in Brewing Industry:
Ammonium fluoride is used as a preservative and disinfectant in the brewing industry, ensuring the quality and safety of the final product.
Used in Wood Preservation:
Ammonium fluoride is used as a preservative for wood, helping to protect it from decay and insect damage.
Used in Textile Industry:
Ammonium fluoride is used in the textile industry as a mordant, which helps to fix dyes to the fabric and improve the colorfastness of the final product.
Used in Glass Etching and Frosting:
Ammonium fluoride is used as a glass etching agent and for frosting glass, providing a decorative effect and enhancing the appearance of glass products.
Used in Rare Metal Extraction:
Ammonium fluoride is used for extracting rare metals, contributing to the production of valuable materials for various industries.
Used in Solid-State Lasers and Photoluminescence:
Ammonium fluoride is employed in the synthesis of NaHoF4 and NaEuF4, which are important for solid-state lasers and photoluminescence applications.
Used in Hydrothermal Synthesis:
Ammonium fluoride is used in a new hydrothermal synthesis of complex fluorides, such as NaHoF4 and NaEuF4, which have potential applications in various fields due to their unique properties.
Used in Organic Synthesis:
The fluoride ion in ammonium fluoride is used as a base and nucleophile in organic synthesis, facilitating various chemical reactions and the production of different compounds.
Physical and Chemical Properties:
Ammonium fluoride is a white, deliquescent, crystalline solid that occurs in various forms, such as granular powder, needles, leaflets, or hexagonal prism. It has a density of 1.009 g/cm3 at 25°C and decomposes upon heating. It is highly soluble in cold water but decomposes in hot water. Ammonium fluoride is slightly soluble in alcohol and insoluble in liquid ammonia. It appears as colorless phyllodes or needle-like crystals and forms hexagonal columnar crystals after sublimation. The aqueous solution of ammonium fluoride is acidic.
Ammonium hydrogen fluoride
At room temperature, ammonium hydrogen fluoride appears as white or colorless orthorhombic crystal with slight sour. It is poisonous! It is slightly soluble in alcohol, easily soluble in cold water while subjecting to decomposition in hot water. Its aqueous solution is strongly acidic. It is obtained through the neutralization between the anhydrous hydrofluoric acid and ammonia. It can corrode glass and is corrosive to the skin. It can be used as a chemical reagent, glass etching agent (with participation of hydrofluoric acid), disinfectants and preservatives in fermentation industry, solvent for making metal beryllium via beryllium oxide and surface treatment agent of silicon steel sheet. It can also be used for the manufacturing of ceramics, magnesium alloy, the cleaning and scaling of boiler feed water systems and steam generating system as well as the acid treatment agent for oil sand. It is also used as the component of alkylation and isomerization catalyst.
The production process of ammonium hydrogen fluoride is generally first generating ammonium fluoride followed by further sending through hydrogen fluoride to generate ammonium hydrogen fluoride. If not properly managed, it will become a mixture of ammonium fluoride and ammonium hydrogen fluoride with ammonium fluoride being easily decomposed into ammonium hydrogen fluoride.
This information is edited by Xiongfeng Dai from lookchem.
Toxicity
This product is toxic. The operator must wear protective equipment. See the remaining protective measures in the part of ammonium hydrogen fluoride.
Toxicity
Grading toxic.
Production method
Liquid-phase method: to lead or plastic container, put certain amount of hydrofluoric acid. Cool water in the outer container and slowly introduce ammonia gas under stirring until the pH value of reaction solution reaches about 4. The reaction liquid further goes through cooling and crystallization, centrifugation, air drying to obtain ammonium fluoride products.
NH3 + HF → NHF
Acute toxicity
Intraperitoneal-rat LD50: 31 mg/kg; subcutaneous-Fox LDL0: 280 mg/kg.
Flammability and hazard characteristics
It release flammable ammonia gas upon thermal decomposition; in case of acid, it releases toxic hydrogen fluoride gas.
Storage characteristics
Treasury: ventilation, low-temperature and drying; store it separately from acids, bases, food and CLF3.
Professional standards
TWA 2.5 mg (fluorine)/cubic meter; STEL 5 mg (fluorine)/cubic meter.
Air & Water Reactions
Dissolves in water and forms dilute solution of hydrofluoric acid. May corrode glass, cement, and most metals [USCG, 1999]. Water soluble.
Reactivity Profile
Salts, basic, such as Ammonium fluoride, are generally soluble in water. The resulting solutions contain moderate concentrations of hydroxide ions and have pH's greater than 7.0. They react as bases to neutralize acids. These neutralizations generate heat, but less or far less than is generated by neutralization of the bases in reactivity group 10 (Bases) and the neutralization of amines. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.
Health Hazard
Inhalation of dust may cause irritation of respiratory system. Ingestion is harmful; readily soluble fluorides may be fatal if relatively small quantities are swallowed. Contact with eyes causes local irritation of the mucous membrane. Contact with skin may cause burns. High concs. of fluorine in the urine have been reported following skin contact.
Safety Profile
Poison by subcutaneous and intraperitoneal routes. See also FLUORIDES. When heated to decomposition it emits very toxic fumes of F-, NO,, and NH3. Incompatible with ClF3
Potential Exposure
Ammonium fluoride is used in printing
and dyeing textiles; glass etching, moth-proofing and
wood preserving; in analytical chemistry, agriculture, antiseptic
in brewing.
Shipping
UN2505 Ammonium fluoride, Hazard Class:
6.1; Labels: 6.1-Poisonous materials.
Incompatibilities
Acids, alkalis, chlorine trifluoride.
Corrodes glass, cement, most metals.
Waste Disposal
Consult with environmental
regulatory agencies for guidance on acceptable disposal
practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing
storage, transportation, treatment, and waste disposal.
Check Digit Verification of cas no
The CAS Registry Mumber 12125-01-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,2,1,2 and 5 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 12125-01:
(7*1)+(6*2)+(5*1)+(4*2)+(3*5)+(2*0)+(1*1)=48
48 % 10 = 8
So 12125-01-8 is a valid CAS Registry Number.
InChI:InChI=1/FH.H3N/h1H;1H3
