121411-14-1

Basic information

• Product Name: (4-Methoxy-phenyl)-[(S)-1-(4-nitro-phenyl)-2-((R)-toluene-4-sulfinyl)-ethyl]-amine
• CAS NO: 121411-14-1
• Molecular Weight: 410.494
• Mol File: 121411-14-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (4-Methoxy-phenyl)-[(S)-1-(4-nitro-phenyl)-2-((R)-toluene-4-sulfinyl)-ethyl]-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Methoxy-phenyl)-[(S)-1-(4-nitro-phenyl)-2-((R)-toluene-4-sulfinyl)-ethyl]-amine(121411-14-1)
• EPA Substance Registry System: (4-Methoxy-phenyl)-[(S)-1-(4-nitro-phenyl)-2-((R)-toluene-4-sulfinyl)-ethyl]-amine(121411-14-1)

Safety Data

• Hazardous Substances Data: 121411-14-1(Hazardous Substances Data)

Upstream product

• 1519-39-7 (R)-methyl p-tolyl sulfoxide 
• 39963-93-4 (E)-4-methoxy-N-(4-nitrobenzylidene)aniline 
• 104-94-9 4-methoxy-aniline 
• 555-16-8 4-nitrobenzaldehdye 
• 5455-87-8 4-methoxy-N-(4-nitrobenzylidene)aniline 

Relevant articles and documents

On the additions of lithium methyl p-tolyl sulfoxide to N-(PMP)arylaldimines

The results presented in this paper confirm that the stereochemical outcome of the reversible additions of lithium (R)-methyl p-tolyl sulfoxide to N-arylidene-p-anisidines (N-PMP imines) depends on: (a) the reaction conditions used and (b) the electronic properties of the arylidene moiety on the starting imine. In particular, we show that under kinetic control (-70 °C) the additions involving electron-rich N-arylidene groups occur with very high stereocontrol in favor of the (2S,RS)-diastereomers, whereas an electron-deficient group favors the opposite stereochemical outcome. Based on the observations above, a mechanistic hypothesis is proposed.