121697-66-3

Basic information

• Product Name: 3-pyridylacetylene
• Synonyms: 3-PYRIDYLACETYLENE
• CAS NO: 121697-66-3
• Molecular Formula: C7H5N
• Molecular Weight: 103.12
• Mol File: 121697-66-3.mol
• Article Data: 297

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-pyridylacetylene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-pyridylacetylene(121697-66-3)
• EPA Substance Registry System: 3-pyridylacetylene(121697-66-3)

Safety Data

• Hazardous Substances Data: 121697-66-3(Hazardous Substances Data)

Upstream product

• 462-08-8 pyridin-3-ylamine 
• 626-55-1 3-Bromopyridine 
• 59-67-6 nicotinic acid 
• 70-55-3 toluene-4-sulfonamide 
• 98-10-2 benzenesulfonamide 
• 108-99-6 3-Methylpyridine 
• 98-92-0 nicotinamide 
• 22083-74-5 3-(1-methyl-pyrrolidin-2-yl)-pyridine 
• 110-86-1 pyridine 
• 460-19-5 ethanedinitrile 
• 500-22-1 3-pyridinecarboxaldehyde 
• 67-66-3 chloroform 
• 504-29-0 2-aminopyridine 
• 151-50-8 potassium cyanide 

Downstream Products

• 35779-35-2 di-3-pyridylmethanone 
• 59576-33-9 2-(2-pyridinyl)-1-(3-pyridinyl)ethanone 
• 37128-50-0 (2-methyl-1H-indol-3-yl)-3-pyridinylmethanone 
• 37760-49-9 3-phenyl-5-(pyridin-3-yl)-1,2,4-oxadiazole 
• 5585-14-8 3,4-diphenyl-furazan 2-oxide 
• 63697-67-6 (E)-2-((2-(pyridin-3-yl)hydrazono)methyl)pyridine 
• 7247-93-0 3-cyano-1-methylpyridinium chloride 
• 1701-72-0 1-(pyridin-3-yl)pentan-1-one 
• 51227-29-3 2-methyl-1-(pyridin-3-yl)propan-1-one 
• 1701-70-8 1-pyridin-3-yl-butan-1-one 
• 120445-71-8 Pyridin-3-aldehyd-semicarbazon 
• 6302-53-0 2-(pyridin-3-yl)imidazoline 
• 32622-22-3 N-phenylnicotinimidamide 
• 16585-32-3 C-phenyl-C-pyridin-3-yl-methyleneamine 

Relevant articles and documents

Palladium-catalyzed synthesis of nitriles from N-phthaloyl hydrazones

The Pd-catalyzed transformation of N-phthaloyl hydrazones into nitriles involving the cleavage of an N-N bond is reported. The use of N-heterocyclic carbene as a ligand is essential for the success of the reaction. N-Phthaloyl hydrazones prepared from aromatic aldehydes or cyclobutanones are applicable to this transformation, which gives aryl or alkenyl nitriles, respectively.

Bis-morpholinophosphorylchloride, a novel reagent for the conversion of primary amides into nitriles

Bis-morpholinophosphorylchloride (Bmpc), in the presence of a base, is an efficient dehydrating agent for both aromatic and aliphatic primary amides, and gives corresponding nitriles under mild conditions in god yields and purity. During the reaction the enantiomeric integrity remains intact.

METHOD FOR PRODUCING NITRILE

The present invention provides a method of producing a nitrile from a primary amide, characterized in that the primary amide is subjected to a dehydration reaction in a supercritical fluid in the presence of an acid catalyst. The present invention achieves the object of reducing the corrosion of a reactor and the thermal decomposition of raw materials, as well as provides the effect of improving the reaction rate and nitrile selectivity.